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How can we link the critical observations performed at autopsy with the events that occur over the previous twenty years of Alzheimer’s Disease? This is the problem posed to a group of our colleagues who are using state-of-the-art neural imaging methods in patients and in animal models to illuminate the natural history of the disease – in the living brain.
Neuropathology of Alzheimer’s Disease as Seen in Fixed Tissues.-Cerebrospinal Fluid Biomarkers for the Diagnosis of Alzheimer’s Disease.- The Living Brain and Alzheimer’s Disease.- In Vivo Imaging of Alzheimer Pathology in Transgenic Mice Using Multiphoton Microscopy.- In Vivo Magnetic Resonance of Amyloid Plaques in Alzheimer’s Disease Model Mice.- Measuring Progression in Alzheimer’s Disease Using Serial MRI: 4D MRI.- Validating MRI Measures of Disease Stage and Progression in Alzheimer’s Disease.- Dynamic Mapping of Alzheimer’s Disease.- Development of Benzothiazole Amyloid-Imaging Agent (PIB) in Alzheimer’s Disease Patients and Healthy Volunteers.- Mild Cognitive Impairment (MCI): Predicting Conversion to Clinically Probable Alzheimer’s Disease with Fluoro-Deoxy-Glucose PET.- Subject Index