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Written by leading experts in the fields Neuroscience and Endocrinology
Provides topical research results
Another excellent group of authors and their chapters collected by Fondation Ipsen
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
Content Level »Research
Keywords »autophagy - cellular defense - cytoplasmic degradation - neuronal control - protein homeostasis