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High Calorie Diet and the Human Brain

Metabolic Consequences of Long-Term Consumption

  • Book
  • © 2015

Overview

Authors:
  1. Akhlaq A. Farooqui

    1. Columbus, USA

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  • Provides current and comprehensive information on neuro inflammation and oxidative stress caused by the consumption of a high-calorie diet in visceral and neurological disorders
  • Unique in the fields of food sciences and neurosciences
  • Covers signal transduction processes associated with the contribution of a high-calorie diet on neuro inflammation and oxidative stress in the pathogenesis of age-related neurological disorders

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Effect of Long Term Consumption of High Calorie Diet and Calorie Restriction on Human Health

    • Akhlaq A. Farooqui
    Pages 1-28

  3. Neurochemical Effects of Long Term Consumption of High Fat Diet

    • Akhlaq A. Farooqui
    Pages 29-76

  4. Neurochemical Effects of Long Term Consumption of Simple Carbohydrates

    • Akhlaq A. Farooqui
    Pages 77-117

  5. Effects of Long Term Consumption of Animal Proteins in the High Calorie Diet

    • Akhlaq A. Farooqui
    Pages 119-132

  6. Effect of Soft Drink Consumption on Human Health

    • Akhlaq A. Farooqui
    Pages 133-158

  7. Contribution of Salt in Inducing Biochemical Changes in the Brain

    • Akhlaq A. Farooqui
    Pages 159-192

  8. Importance and Roles of Fiber in the Diet

    • Akhlaq A. Farooqui
    Pages 193-218

  9. Effects of the High Calorie Diet on the Development of Chronic Visceral Disease

    • Akhlaq A. Farooqui
    Pages 219-244

  10. Effects of Long Term Consumption of High Calorie Diet on Neurological Disorders

    • Akhlaq A. Farooqui
    Pages 245-275

  11. Perspective and Direction for Future Research: Modification of High Calorie Diet Needed for Optimal Health of Human Visceral and Brain Tissues

    • Akhlaq A. Farooqui
    Pages 277-298

  12. Back Matter

    Pages 299-308
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Keywords

About this book

The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.

Authors and Affiliations

  • Columbus, USA

    Akhlaq A. Farooqui

About the author

Akhlaq A. Farooqui is a leader in the field of signal transduction processes, lipid mediators, phospholipases A2, glutamate neurotoxicity, phytochemicals and human health and neurological disorders. He has published cutting edge research on the role of phospholipases A2 in signal transduction processes, generation and identification of lipid mediators during neurodegeneration by lipidomics and has studied the involvement of glycerophospholipid, sphingolipid- and cholesterol-derived lipid mediators in kainic acid neurotoxicity, an experimental model of neurodegenerative diseases.

Bibliographic Information

  • Book Title: High Calorie Diet and the Human Brain

  • Book Subtitle: Metabolic Consequences of Long-Term Consumption

  • Authors: Akhlaq A. Farooqui

  • DOI: https://doi.org/10.1007/978-3-319-15254-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-15253-0Published: 07 April 2015

  • Softcover ISBN: 978-3-319-35848-2Published: 08 October 2016

  • eBook ISBN: 978-3-319-15254-7Published: 25 March 2015

  • Edition Number: 1

  • Number of Pages: XVIII, 308

  • Number of Illustrations: 52 b/w illustrations, 31 illustrations in colour

  • Topics: Neurochemistry, Food Science

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