Skip to main content
SpringerLink
Log in

Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain

  • Book
  • © 2014

Overview

Editors:
  1. Vladimir Parpura

    1. Department of Neurobiology CIRC 429, University of Alabama, Birmingham, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Arne Schousboe

    1. Faculty of Health and Medical Sciences, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Alexei Verkhratsky

    1. Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Suitable for advanced and graduate courses on the roles of glutamate and ATP in metabolism and signaling
  • Only current book on this highly researched topic
  • Contributions from leading experts in cell metabolism, intracellular signaling and neurotransmission

Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 11)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (11 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Glutamate and ATP: The Crossroads of Signaling and Metabolism in the Brain

    • Alexei Verkhratsky, Arne Schousboe, Vladimir Parpura
    Pages 1-12

  3. Glutamate Metabolism in the Brain Focusing on Astrocytes

    • Arne Schousboe, Susanna Scafidi, Lasse K. Bak, Helle S. Waagepetersen, Mary C. McKenna
    Pages 13-30

  4. Glycogenolysis and Purinergic Signaling

    • Leif Hertz, Junnan Xu, Liang Peng
    Pages 31-54

  5. Purinergic and Glutamatergic Receptors on Astroglia

    • Alexei Verkhratsky, Geoffrey Burnstock
    Pages 55-79

  6. Regulated Exocytosis in Astrocytes is as Slow as the Metabolic Availability of Gliotransmitters: Focus on Glutamate and ATP

    • Nina Vardjan, Marko Kreft, Robert Zorec
    Pages 81-101

  7. Adenosine and Glutamate in Neuroglial Interaction: Implications for Circadian Disorders and Alcoholism

    • Christina L. Ruby, Katheryn M. O’Connor, Jennifer Ayers-Ringler, Doo-Sup Choi
    Pages 103-119

  8. Purinergic Receptor Stimulation Decreases Ischemic Brain Damage by Energizing Astrocyte Mitochondria

    • Naomi L. Sayre, Yanan Chen, Mikaela Sifuentes, Brian Stoveken, James D. Lechleiter
    Pages 121-150

  9. Excitotoxicity and Mitochondrial Dysfunction Underlie Age-Dependent Ischemic White Matter Injury

    • Selva Baltan
    Pages 151-170

  10. Role of Astrocytes in Delayed Neuronal Death: GLT-1 and its Novel Regulation by MicroRNAs

    • Yi-Bing Ouyang, Lijun Xu, Siwei Liu, Rona G. Giffard
    Pages 171-188

  11. Ca2+ Signaling in Astrocytes and its Role in Ischemic Stroke

    • Shinghua Ding
    Pages 189-211

  12. Pathological Potential of Astroglial Purinergic Receptors

    • Heike Franke, Peter Illes
    Pages 213-256

  13. Back Matter

    Pages 257-261
    Download chapter PDF
Back to top

Keywords

About this book

ATP acts as main energy source and is pivotal for numerous signaling cascades both inside the cells (by fuelling various transport systems and donating phosphate groups) and between the cells (by chemical transmission). Similarly glutamate acts as an important molecule for both intercellular signaling though glutamatergic transmission and cell energetics by contributing to ATP production.

In this collection of chapters, written by the leading experts in the field of cell metabolism and energetics, intracellular signaling and neurotransmission we covered various aspects of the interfacing between these two fundamental molecules. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry.

Editors and Affiliations

  • Department of Neurobiology CIRC 429, University of Alabama, Birmingham, USA

    Vladimir Parpura

  • Faculty of Health and Medical Sciences, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark

    Arne Schousboe

  • Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

    Alexei Verkhratsky

Bibliographic Information

  • Book Title: Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain

  • Editors: Vladimir Parpura, Arne Schousboe, Alexei Verkhratsky

  • Series Title: Advances in Neurobiology

  • DOI: https://doi.org/10.1007/978-3-319-08894-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2014

  • Hardcover ISBN: 978-3-319-08893-8Published: 30 September 2014

  • Softcover ISBN: 978-3-319-37645-5Published: 23 August 2016

  • eBook ISBN: 978-3-319-08894-5Published: 18 September 2014

  • Series ISSN: 2190-5215

  • Series E-ISSN: 2190-5223

  • Edition Number: 1

  • Number of Pages: XVII, 261

  • Number of Illustrations: 22 b/w illustrations, 39 illustrations in colour

  • Topics: Neurosciences, Neurobiology

Publish with us

Policies and ethics

Back to top

Search

Navigation