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Zebrafish Protocols for Neurobehavioral Research

  • Book
  • © 2012

Overview

Editors:
  1. Allan V. Kalueff

    1. Neuroscience Program, Department of Pharmacology, Tulane University, New Orleans, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Adam Michael Stewart

    1. , Department of Pharmacology, Tulane University, New Orleans, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes protocols for both larval and adult zebrafish in order to cover the gamut of their potential in neurobehavioral research
  • Features clear, step-by-step techniques, proven successful in laboratories around the world
  • Contains key tips and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 66)

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Table of contents (27 protocols)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Larval Zebrafish Models

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Measuring Larval Zebrafish Behavior: Locomotion, Thigmotaxis, and Startle

      • William H. J. Norton
      Pages 3-20

    3. The Light–Dark Preference Test for Larval Zebrafish

      • Peter J. Steenbergen, Michael K. Richardson, Danielle L. Champagne
      Pages 21-35

    4. Assessment of Thigmotaxis in Larval Zebrafish

      • Stephanie J. Schnörr, Peter J. Steenbergen, Michael K. Richardson, Danielle L. Champagne
      Pages 37-51

    5. Zebrafish and Drug Development: A Behavioral Assay System for Probing Nicotine Function in Larval Zebrafish

      • Henning Schneider, Eric W. Klee, Karl J. Clark, Andrew M. Petzold, Vanessa L. Mock, Julia M. Abarr et al.
      Pages 53-70

    6. Olfactory-Evoked Activity Assay for Larval Zebrafish

      • Ganive Bhinder, Keith B. Tierney
      Pages 71-84

    7. Qualitative and Quantitative Measurements of the Optokinetic Response in Larval Zebrafish

      • Kaspar P. Mueller, Stephan C. F. Neuhauss
      Pages 85-94

    8. Automated Imaging of Visual Recognition Memory in Larval Zebrafish

      • Ruth M. Colwill, Robbert Creton
      Pages 95-106

    9. Automated Conditioning in Larval Zebrafish

      • Ruey-Kuang Cheng, Suresh Jesuthasan
      Pages 107-120

    10. Methods to Quantify Basal and Stress-Induced Cortisol Response in Larval Zebrafish

      • Peter J. Steenbergen, Juriaan R. Metz, Gert Flik, Michael K. Richardson, Danielle L. Champagne
      Pages 121-141

  3. Adult Zebrafish Models

    1. Front Matter

      Pages 143-143
      Download chapter PDF

    2. A Method for Sorting Zebrafish on the Exploratory-Boldness Behavioral Axis

      • Cory D. Sailer, Sonny J. Radenic, Brian D. Wisenden
      Pages 145-151

    3. Nocifensive Behavior in Adult and Larval Zebrafish

      • Monica Gomes Lima, Caio Maximino, Evander de Jesus Oliveira Batista, Karen Renata Matos Oliveira, Anderson Manoel Herculano
      Pages 153-166

    4. Use of a Split Depth and Visual Cliff Apparatus to Measure the Diving Response in Zebrafish

      • Rachel Blaser, Kelly Goldsteinholm
      Pages 167-180

    5. Adapting the Open Field Test to Assess Anxiety-Related Behavior in Zebrafish

      • John Godwin, Susanna Sawyer, Florence Perrin, Sarah E. Oxendine, Zachary D. Kezios
      Pages 181-189

    6. Behavioral and Pharmacological Aspects of Anxiety in the Light/Dark Preference Test

      • Juliana Araujo, Caio Maximino, Thiago Marques de Brito, Annanda Waneza Batista da Silva, Karen Renata Matos Oliveira, Evander de Jesus Oliveira Batista et al.
      Pages 191-202

    7. A High-Throughput and Inexpensive Assay for Anxiety-Related Behaviors in the Zebrafish, Based on Place Preference and Latency to Feed

      • Barrie D. Robison, Maia J. Benner, Matthew L. Singer, Mary E. Oswald
      Pages 203-215

    8. Automated Tracking of Zebrafish Shoals and the Analysis of Shoaling Behavior

      • Noam Miller, Robert Gerlai
      Pages 217-230

    9. Assessing Social Behavior Phenotypes in Adult Zebrafish: Shoaling, Social Preference, and Mirror Biting Tests

      • Mimi Pham, Jolia Raymond, Jonathan Hester, Evan Kyzar, Siddharth Gaikwad, Indya Bruce et al.
      Pages 231-246
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Keywords

About this book

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research.  Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders.  Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.

Editors and Affiliations

  • Neuroscience Program, Department of Pharmacology, Tulane University, New Orleans, USA

    Allan V. Kalueff

  • , Department of Pharmacology, Tulane University, New Orleans, USA

    Adam Michael Stewart

Bibliographic Information

  • Book Title: Zebrafish Protocols for Neurobehavioral Research

  • Editors: Allan V. Kalueff, Adam Michael Stewart

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-61779-597-8

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-596-1Published: 06 June 2012

  • Softcover ISBN: 978-1-4939-6002-6Published: 23 August 2016

  • eBook ISBN: 978-1-61779-597-8Published: 05 June 2012

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XVII, 357

  • Number of Illustrations: 62 b/w illustrations, 22 illustrations in colour

  • Topics: Neurosciences, Animal Models

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