Editors:
- Serves as a comprehensive and valuable reference for those studying motor disorders
- Provides appropriate models and assessment tools
- Includes clear, easy to follow methods with expert implementation advice
Part of the book series: Neuromethods (NM, volume 61)
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Table of contents (21 protocols)
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Front Matter
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Generic Methods of Assessment
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Front Matter
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Dopamine Systems
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Front Matter
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About this book
Movement is the way that animals interact with their environment and is under the organization and complex control of the brain and spinal cord. Multiple central nervous systems, including cortex, basal ganglia, cerebellum, and brainstem, interact to provide precise motor control and integration. Damage or disease within these systems cause profound motor disturbances in man, which can be effectively modeled in animals to develop a better understanding and treatment of the human condition. Animal Models of Movement Disorders introduces a variety of methods and techniques used to model and assess motor function in experimental animals from lower orders, such as drosophila and c. elegans, through vertebrate species including fish, to mammals, such as rodents and non-human primates. The most advanced contemporary models in each system are presented at multiple levels of analysis from molecular and genetic modeling, lesions, anatomy, neurochemistry, to imaging and behavior. Volume I contains general methods of movement disorder assessment as well as an extensive section on dopamine systems.Â
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Comprehensive and meticulous, Animal Models of Movement Disorders serves as a valuable reference for those studying motor disorders by covering methodologies in detail and providing the information necessary to consider both the appropriate models and assessment tools that can most informatively answer the key experimental issues in the field.Editors and Affiliations
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, Welsh School of Pharmacology, Cardiff University, Cardiff, United Kingdom
Emma L. Lane
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School of Biosciences, Brain Repair Group, Cardiff University, Cardiff, United Kingdom
Stephen B. Dunnett
Bibliographic Information
Book Title: Animal Models of Movement Disorders
Book Subtitle: Volume I
Editors: Emma L. Lane, Stephen B. Dunnett
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-61779-298-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-297-7Published: 15 September 2011
Softcover ISBN: 978-1-4939-6240-2Published: 23 August 2016
eBook ISBN: 978-1-61779-298-4Published: 15 September 2011
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XV, 447
Topics: Neurosciences, Neurology, Animal Models