Editors:
- Most up-to-date volume to focus on the mechanisms of cell injury and cell survival in the brain, with special emphasis on development and early life, in relation to hypoxia and ischemia in the brain.
- Comments on the developmental stages of the brain is the major societal and economic burden of the affliction when it occurs in early life.
Part of the book series: Contemporary Clinical Neuroscience (CCNE)
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Table of contents (17 chapters)
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Front Matter
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Ion Channels, Transporters and Excitotoxicity
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Reactive Oxygen Species, and Gene Expression to Behavior
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Back Matter
About this book
Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development.
This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.
Editors and Affiliations
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University of California, San Diego
Gabriel G. Haddad
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Rady Children's Hospital, San Diego
Gabriel G. Haddad
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Emory University, Atlanta
Shan Ping Yu
Bibliographic Information
Book Title: Brain Hypoxia and Ischemia
Editors: Gabriel G. Haddad, Shan Ping Yu
Series Title: Contemporary Clinical Neuroscience
DOI: https://doi.org/10.1007/978-1-60327-579-8
Publisher: Humana Totowa, NJ
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-60327-578-1Published: 12 December 2008
Softcover ISBN: 978-1-61737-914-7Published: 09 December 2010
eBook ISBN: 978-1-60327-579-8Published: 06 January 2009
Series ISSN: 2627-535X
Series E-ISSN: 2627-5341
Edition Number: 1
Number of Pages: XII, 268
Number of Illustrations: 21 b/w illustrations, 26 illustrations in colour
Topics: Neurosciences, Human Physiology, Neurology, Neurobiology