Editors:
- Provides an easily accessible reference for emerging animal models of epilepsy written by leading researchers in the field
- Details the latest innovations and methodologies currently being applied in the field of epilepsy research
- Covers a wide range of species and approaches
- Presents a variety of experimental strategies, covering simple model organisms, imaging and modeling technologies, gene therapy and genetic approaches to animal model development
- Moves beyond traditional animal models to encompass organisms and strategies that are at the cutting-edge of neuroscience
- Includes supplementary material: sn.pub/extras
Part of the book series: Neuromethods (NM, volume 40)
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Table of contents (14 protocols)
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Front Matter
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Back Matter
About this book
With its complex anatomical, molecular, electrophysiological and behavioral components, epilepsy provides the neuroscientist with nearly boundless opportunities to examine basic neurobiological mechanisms. In Animal Models of Epilepsy: Methods and Innovations, prominent investigators in the field examine several novel models of epilepsy in mice as well as in genetically tractable "simple" species such as Drosophila melanogaster (fruit flies), Caenorhabditis elegans (worms), Xenopus laevis (tadpoles) and Danio rerio (zebrafish). While covering some traditional models, the volume also explores the newest innovations like modeling seizure activity in silica and advanced strategies for seizure detection and gene therapy. As a volume in the successful Neuromethods™ series, the chapters provide clear, step-by-step protocols and thought-provoking reviews of the most recent advancements in the field.
Comprehensive and cutting-edge, Animal Models of Epilepsy: Methods and Innovations is an ideal guide for scientists who wish to expand our understanding of the pathogenesis of this neurological disorder.
Reviews
From the reviews:
“As a clinical epileptologist interested in fundamental aspects of epilepsy, I obtained a thorough update on the several frontiers of current epilepsy research from this lucid volume. Basic scientists will profit from these 14 distinct and succinct reviews that also treat methodology and pitfalls in detail. Thus, this work is recommended for basic science and clinical epileptologists as well as students of these disciplines.” (Warren T. Blume, Canadian Journal of Neurological Sciences, Vol. 37 (4), July, 2010)Bibliographic Information
Book Title: Animal Models of Epilepsy
Book Subtitle: Methods and Innovations
Editors: Scott C. Baraban
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-60327-263-6
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-60327-262-9Published: 29 May 2009
Softcover ISBN: 978-1-4939-6114-6Published: 23 August 2016
eBook ISBN: 978-1-60327-263-6Published: 12 June 2009
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XIII, 276
Number of Illustrations: 39 b/w illustrations, 19 illustrations in colour
Topics: Neurosciences, Neurology, Animal Models