Skip to main content
SpringerLink
Log in

The GABA Receptors

  • Book
  • © 2007

Overview

Editors:
  1. S. J. Enna

    1. Departments of Molecular and Integrative Physiology and of Pharmcology, Toxicology and Therapeutics, University of Kansas, Kansas City

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Hanns Möhler

    1. Department of Chemistry and Applied Biosciecnes Swiss Federal Institute of Technology (ETH), Institute of Pharmacology University of Zurich, Zurich
      Collegium Helveticum, Zurich, Switzerland

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors
  • Chapters written world-renowned leaders of the field

Part of the book series: The Receptors (REC)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. The GABA Receptors

    • S. J. Enna
    Pages 1-21

  3. Functional Relevance of GABAA-Receptor Subtypes

    • Hanns Möhler
    Pages 23-39

  4. Trafficking of Postsynaptic GABAA Receptors by Receptor-Associated Proteins

    • Xu Yuan, Bernhard Lüscher
    Pages 41-67

  5. Subunit Composition and Structure of GABAA-Receptor Subtypes

    • Werner Sieghart
    Pages 69-86

  6. Differential Activation of GABAA-Receptor Subtypes

    • Mark Farrant
    Pages 87-110

  7. GABAA-Receptor Mutations Associated With Idiopathic Generalized Epilepsies and Febrile Seizures

    • Robert L. Macdonald, Jing-Qiong Kang, Martin J. Gallagher, Hua-Jun Feng
    Pages 111-142

  8. Abuse and Dependence Liability of GABAA-Receptor Modulators

    • James K. Rowlett, Angela N. Duke, Donna M. Platt
    Pages 143-168

  9. Mechanisms of GABAA and GABAB Receptor Gene Regulation and Cell Surface Expression

    • David H. Farb, Janine L. Steiger, Stella C. Martin, Maria C. Gravielle, Terrell T. Gibbs, Shelley J. Russek
    Pages 169-238

  10. Chemistry of GABAB Modulators

    • Wolfgang Froestl, Nigel G. Cooke, Stuart J. Mickel
    Pages 239-251

  11. The Unusual Functioning of the GABAB-Receptor Heterodimer

    • Andrés Couve, Stephen J. Moss, Menelas N. Pangalos
    Pages 253-271

  12. Characteristics of GABAB Receptor Mutant Mice

    • Jim Yu-Hsiang Tiao, Bernhard Bettler
    Pages 273-287

  13. GABAB Receptor ad a Potential Therapeutic Target

    • Norman G. Bowery
    Pages 289-312

  14. Back Matter

    Pages 313-325
    Download chapter PDF
Back to top

Keywords

About this book

This volume is the third edition of a monograph series that was first published in 1983. The demand for this work is a testament to the impact of studies on -aminobutyric acid (GABA) receptors on the basic understanding of synaptic transmission and on defining the clinical importance of the neurotransmitter system. Chronicled in The GABA Receptors, Third Edition, are the advances made in understanding the molecular and pharmacological properties of GABA A and GABA receptors since the topic was last reviewed in 1996. Particular B emphasis is placed on describing the assembly, structure, and function of GABA B sites, the first heterodimeric G protein-coupled receptors identified in vivo. In addition, there are reports dealing with the subunit composition, trafficking, and pharmacological selectivity of GABA receptors. Aside from providing A insights into the fundamental properties of ligand-gated ion channels and second messenger systems, the findings detailed in this work point the way for developing novel therapeutics capable of more selectively manipulating these transmitter sites.

Editors and Affiliations

  • Departments of Molecular and Integrative Physiology and of Pharmcology, Toxicology and Therapeutics, University of Kansas, Kansas City

    S. J. Enna

  • Department of Chemistry and Applied Biosciecnes Swiss Federal Institute of Technology (ETH), Institute of Pharmacology University of Zurich, Zurich

    Hanns Möhler

  • Collegium Helveticum, Zurich, Switzerland

    Hanns Möhler

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation