The Cell Cycle in the Central Nervous System

1. Front Matter

   Pages i-xvii

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2. Cell Cycle During the Development of the Mammalian Central Nervous System

   1. Front Matter

      Pages 1-1

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   2. Methodological Considerations in the Evaluation of the Cell Cycle in the Central Nervous System

      • Richard A. Prayson

      Pages 3-12

   3. Neural Stem Cells

      • Philippe Taupin

      Pages 13-22

   4. Progenitors and Precursors of Neurons and Glial Cells

      • Monika Bradl

      Pages 23-29

   5. Vasculogenesis and Angiogenesis

      • Gerald A. Grant, Damir Janigro

      Pages 31-41

   6. Neuronal Migration and Malformations of Cortical Development

      • Giorgio Battaglia, Stefania Bassanini

      Pages 43-55

3. Postnatal Development of Neurons and Glia

   1. Front Matter

      Pages 57-57

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   2. Genome-Wide Expression Profiling of Neurogenesis in Relation to Cell Cycle Exit

      • P. Roy Walker, Dao Ly, Qing Y. Liu, Brandon Smith, Caroline Sodja, Marilena Ribecco et al.

      Pages 59-70

   3. Neurogenesis and Apoptotic Cell Death

      • Klaus van Leyen, Seong-Ryong Lee, Michael A. Moskowitz, Eng H. Lo

      Pages 71-79

   4. Ion Channels and the Cell Cycle

      • Annarosa Arcangeli, Andrea Becchetti

      Pages 81-94

   5. Nonsynaptic GABAergic Communication and Postnatal Neurogenesis

      • Xiuxin Liu, Anna J. Bolteus, Angélique Bordey

      Pages 95-104

   6. Critical Roles of Ca2+ and K+ Homeostasis in Apoptosis

      • Shan Ping Yu

      Pages 105-118

   7. Mammalian Neural Stem Cell Renewal

      • Yvan Arsenijevic

      Pages 119-139

4. Control of the Cell Cycle and Apoptosis in Glia

   1. Front Matter

      Pages 141-141

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   2. Methods of Determining Apoptosis in Neuro-Oncology

      • Brian T. Ragel, Bardia Amirlak, Ganesh Rao, William T. Couldwell

      Pages 143-161

   3. Cell Cycle, Neurological Disorders, and Reactive Gliosis

      • Kerri L. Hallene, Damir Janigro

      Pages 163-175

   4. Potassium Channels, Cell Cycle, and Tumorigenesis in the Central Nervous System

      • Gabriele Dini, Erin V. Ilkanich, Damir Janigro

      Pages 177-191

5. Adult Neurogenesis: A Mechanism for Brain Repair?

   1. Front Matter

      Pages 193-193

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   2. Enhanced Neurogenesis Following Neurological Disease

      • Philippe Taupin

      Pages 195-206

Cell Cycle in the Central Nervous System overviews the changes in cell cycle as they relate to prenatal and post natal brain development, progression to neurological disease or tumor formation.Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.

• Alzheimer
• Nervous System
• alzheimer's disease
• brain
• central nervous system
• cerebral ischemia
• death
• neurons
• positron emission tomography (PET)
• receptor
• tumor

• The Cleveland Clinic Foundation, Cleveland

  Damir Janigro

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