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Transgenic and Knockout Models of Neuropsychiatric Disorders

  • Book
  • © 2006

Overview

Editors:
  1. Gene S. Fisch

    1. Department of Statistics, Yeshiva University, New York
      Department of Psychology, CUNY/Lehman College, New York

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    You can also search for this editor in PubMed   Google Scholar

  2. Jonathan Flint

    1. Wellcome Trust Centre for Human Genetics, Oxford, UK
      Department of Psychiatry, University of Oxford, Oxford, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Contemporary Clinical Neuroscience (CCNE)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xii
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  2. Introduction and Overview

    1. Front Matter

      Pages 1-1
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    2. Transgenic and Knockout Models of Psychiatric Disorders

      • Gene S. Fisch
      Pages 3-23

    3. Transgenic Mouse Models and Human Psychiatric Disease

      • Jonathan Flint
      Pages 25-43

    4. Transgenic and Knockout Mouse Models

      • Linda J. Hayes, Diana Delgado
      Pages 45-67

    5. If Only They Could Talk

      • Trevor Humby, Lawrence Wilkinson
      Pages 69-83

  3. Transgenic and Knockout Models of Neurocognitive Dysfunction

    1. Front Matter

      Pages 85-85
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    2. Spinocerebellar Ataxia Type 1

      • Harry T. Orr
      Pages 87-99

    3. Mouse Models of Hereditary Mental Retardation

      • Hans Welzl, Patrizia D’Adamo, David P. Wolfer, Hans-Peter Lipp
      Pages 101-125

    4. How Can Studies of Animals Help to Uncover the Roles of Genes Implicated in Human Speech and Language Disorders?

      • Simon E. Fisher
      Pages 127-149

    5. Animal Models of Autism

      • Thomas Bourgeron, Stéphane Jamain, Sylvie Granon
      Pages 151-174

  4. Transgenic and Knockout Models of Neuropsychiatric Dysfunction

    1. Front Matter

      Pages 175-175
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    2. Genetic Mouse Models of Psychiatric Disorders

      • Joseph A. Gogos, Maria Karayiorgou
      Pages 177-191

    3. Animal Models of Psychosis

      • Stephen I. Deutsch, Katrice Long, Richard B. Rosse, Yousef Tizabi, Ronit Weizman, Judy Eller et al.
      Pages 193-220

    4. Animal Models of Anxiety

      • Robert Gerlai, Robert Blanchard, Caroline Blanchard
      Pages 221-236

    5. Modeling Human Anxiety and Depression in Mutant Mice

      • Andrew Holmes, John F. Cryan
      Pages 237-263

    6. Mutant Mouse Models of Bipolar Disorder

      • Anneloes Dirks, Lucianne Groenink, Berend Olivier
      Pages 265-285

  5. Back Matter

    Pages 287-296
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Keywords

About this book

In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, and speech disorders, as well as disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder.

Editors and Affiliations

  • Department of Statistics, Yeshiva University, New York

    Gene S. Fisch

  • Department of Psychology, CUNY/Lehman College, New York

    Gene S. Fisch

  • Wellcome Trust Centre for Human Genetics, Oxford, UK

    Jonathan Flint

  • Department of Psychiatry, University of Oxford, Oxford, UK

    Jonathan Flint

Bibliographic Information

  • Book Title: Transgenic and Knockout Models of Neuropsychiatric Disorders

  • Editors: Gene S. Fisch, Jonathan Flint

  • Series Title: Contemporary Clinical Neuroscience

  • DOI: https://doi.org/10.1007/978-1-59745-058-4

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Humana Press 2006

  • Hardcover ISBN: 978-1-58829-507-1Published: 01 March 2006

  • Softcover ISBN: 978-1-61737-607-8Published: 09 November 2010

  • eBook ISBN: 978-1-59745-058-4Published: 06 November 2007

  • Series ISSN: 2627-535X

  • Series E-ISSN: 2627-5341

  • Edition Number: 1

  • Number of Pages: XII, 296

  • Number of Illustrations: 20 b/w illustrations

  • Topics: Neurosciences

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