Overview
- Includes cutting-edge methods and protocols for the use of a variety of organism models to explore ASD
- Provides both the technical theory and practical aspects needed to achieve successful results in the lab
- Contains key notes and implementation advice from the experts
Part of the book series: Neuromethods (NM, volume 100)
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Table of contents (19 protocols)
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Front Matter
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Organism Models of Autism Spectrum Disorders: Selecting the Good Species
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Modeling Autism Spectrum Disorder at the Brain Level
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Communication and Social Interactions
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Mouse Models of Autism Spectrum Disorders as Defined by DSM-5R
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Keywords
About this book
As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab.
Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.
Reviews
“Aims to assist readers in contemplating and selecting a species to model a circumscribed aspect of the illness, such as a mutation or a neuronal network problem. … Each chapter concludes with citations from the scientific literature which are both timely and relevant. This is an interesting and informative book on modeling aspects of ASD. Researchers in the field will find the approach to studying ASD refreshing and hopeful. This is a valuable contribution to this area of study.” (Michael Joel Schrift, Doody's Book Reviews, May, 2015)
Editors and Affiliations
Bibliographic Information
Book Title: Organism Models of Autism Spectrum Disorders
Editors: Pierre L. Roubertoux
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-4939-2250-5
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2015
Hardcover ISBN: 978-1-4939-2249-9Published: 22 January 2015
Softcover ISBN: 978-1-4939-4219-0Published: 24 September 2016
eBook ISBN: 978-1-4939-2250-5Published: 22 January 2015
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XVIII, 487
Number of Illustrations: 71 b/w illustrations, 27 illustrations in colour
Topics: Neurosciences, Neurology, Animal Models