Overview
- Includes cutting-edge methods and protocols involving the serotonergic system
- Provides vital details essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Neuromethods (NM, volume 95)
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Table of contents (12 protocols)
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Receptor Dimerization
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Manipulation and Analysis of Serotonergic Signaling in Brain Slices
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Mouse Models to Study Serotonin-Associated Behavioral Disorders
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Invertebrate Model Systems
Keywords
About this book
Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na+-dependent serotonin transporter (SERT), this volume provides state of the art methodologies currently applied in serotonin research from leading experts in the field. Serotonin Receptor Technologies describes approaches that vary from molecular biological and biochemical techniques (e.g., regarding receptor dimerization), fluorescence microscopy and imaging applications, flow cytometry, the use of organotypic slice and cell cultures to the generation of genetically modified animal models and the development of sophisticated behavioral tests, thus covering a wide spectrum of techniques to study serotonergic signaling in detail. Written for the popular Neuromethods series, chapters include the kind of detail and practical advice that ensures successful results in the lab.
Authoritative and convenient, Serotonin Receptor Technologies serves to foster both basic and translational research aiming to further deepen our understanding of the various facets of aminergic systems, as well as to aid research on similar problems with related GPCRs and neurotransmitter transporters.
Editors and Affiliations
Bibliographic Information
Book Title: Serotonin Receptor Technologies
Editors: Wolfgang Blenau, Arnd Baumann
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-4939-2187-4
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2015
Hardcover ISBN: 978-1-4939-2186-7Published: 06 December 2014
Softcover ISBN: 978-1-4939-5562-6Published: 23 August 2016
eBook ISBN: 978-1-4939-2187-4Published: 05 December 2014
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XII, 245
Number of Illustrations: 16 b/w illustrations, 35 illustrations in colour
Topics: Neurosciences, Neurochemistry