Overview
- Only book to cover the role of microglia in the healthy brain as well as in pathological conditions
- The most up-to-date research in the subject
- Contributions from leading researchers and emerging experts
- Includes supplementary material: sn.pub/extras
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About this book
These past few years have witnessed a revolution in our understanding of microglia, especially since their roles in the healthy central nervous system (CNS) have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their involvement with diseases. Edited by two pioneers in the field, Marie-Ève Tremblay and Amanda Sierra, Microglia in health and disease aims to share with the broader scientific community some of the recent discoveries in microglia research, from a broad perspective, with a collection of 19 chapters from 52 specialists working in 11 countries across 5 continents.
To set microglia on the stage, the book begins by explaining briefly who they are, what they do in the healthy and diseased CNS, and how they can be studied. The first section describes in more details their physiological roles in the maturation, function, and plasticity of the CNS, across development, adolescence, adulthood, neuropathic pain, addiction, and aging. The second section focuses on their implication in pathological conditions impairing the quality of life: neurodevelopmental and neuropsychiatric disorders, AIDS, and multiple sclerosis; and in leading causes of death: ischemia and stroke, neurodegenerative diseases, as well as trauma and injury.
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Keywords
Table of contents (19 chapters)
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Front Matter
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The General Setting
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Front Matter
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Their Pathological Implications Conditions Impacting on the Quality of Life
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Front Matter
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Editors and Affiliations
Bibliographic Information
Book Title: Microglia in Health and Disease
Editors: Marie-Ève Tremblay, Amanda Sierra
DOI: https://doi.org/10.1007/978-1-4939-1429-6
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media New York 2014
Hardcover ISBN: 978-1-4939-1428-9Published: 23 September 2014
Softcover ISBN: 978-1-4939-4617-4Published: 23 August 2016
eBook ISBN: 978-1-4939-1429-6Published: 22 September 2014
Edition Number: 1
Number of Pages: XIV, 486
Number of Illustrations: 12 b/w illustrations, 20 illustrations in colour
Topics: Neurosciences, Neurobiology, Immunology