The GABA Receptors

1. Front Matter

   Pages i-x

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2. Structure and Function of GABA Reuptake Systems

   • Baruch I. Kanner

   Pages 1-9

3. Diversity in Structure, Pharmacology, and Regulation of GABAA Receptors

   • H. Möhler, D. Benke, J. Benson, B. Lüscher, U. Rudolph, J. M. Fritschy

   Pages 11-36

4. GABAA Receptor Agonists, Partial Agonists, and Antagonists

   • Povl Krogsgaard-Larsen, Bente Frølund, Bjarke Ebert

   Pages 37-81

5. Pharmacology of Mammalian GABAA Receptors

   • Neil Upton, Thomas Blackburn

   Pages 83-120

6. The Interaction of Intravenous Anesthetic Agents with Native and Recombinant GABAA Receptors

   • Jeremy J. Lambert, Delia Belelli, Marco Pistis, Claire Hill-Venning, John A. Peters

   Pages 121-156

7. Electrophysiology of GABAB Receptors

   • Rudolf A. Deisz

   Pages 157-207

8. Pharmacology of Mammalian GABAB Receptors

   • Norman G. Bowery

   Pages 209-236

9. Cellular and Biochemical Responses to GABAB Receptor Activation

   • Martin Cunningham, S. J. Enna

   Pages 237-258

10. Biochemical and Molecular Properties of GABAB Receptors

    • Kinya Kuriyama, Masaaki Hirouchi

    Pages 259-269

11. Chemistry of GABAB Modulators

    • Wolfgang Froestl, Stuart J. Mickel

    Pages 271-296

12. Molecular Biology, Pharmacology, and Physiology of GABAC Receptors

    • Graham A. R. Johnston

    Pages 297-323

13. Back Matter

    Pages 325-332

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In this long-awaited 2nd edition of a classic book, leading neuroscientists critically review the latest advances made in our understanding of the fundamental molecular, biochemical, behavioral, and pharmacological properties of GABA receptors. The distinguished contributors clarify the approaches being taken to identify and develop new therapeutic agents for such neurological and psychiatric disorders as epilepsy, memory loss, affective illnesses, and psychosis. They also examine the therapeutic potential that remains in the cloning and expression of the GABA transporter, and in developing additional agents capable of regulating GABA receptor function. The book will play a key role in further expanding the list of drugs that interact with the GABA neurotransmitter system.

• Activation
• GABA
• biology
• chemistry
• molecular biology
• neurotransmitter
• pharmacology
• physiology
• psychosis
• receptor
• regulation
• research

This is a very good summary of what is known on GABA receptors today and this is of great interest for neurobiologists, pharmacologists and neurophysiologists-ACTA Nuerologica Belgica

• Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical School, Kansas City, USA

  S. J. Enna

• Department of Pharmacology, The Medical School Edgbaston, University of Birmingham, UK

  Norman G. Bowery

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