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Biomedical Sciences - Neuroscience | White Matter Injury in Stroke and CNS Disease

White Matter Injury in Stroke and CNS Disease

Baltan, S., Carmichael, S.Th., Matute, C., Xi, G., Zhang, J.H. (Eds.)

2014, XVI, 592 p. 126 illus., 81 illus. in color.

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  • Provides systematic expert summaries of normal white matter morphology
  • Details white matter injury following stroke and other CNS injuries
  • Contains key notes and implementation advice from the experts

The first book to provide a systematic expert summary of normal white matter morphology as well as white matter injury following stroke and other CNS injuries. White matter injury can result from both ischemic and hemorrhagic stroke as well as a host of other CNS diseases and conditions such as neonatal injuries, neurodegenerative disorders including Alzheimer's disease, traumatic brain injuries, carbon monoxide poisoning, and drug or alcohol overdoses. The extent of white matter injury is extremely important to patient outcomes. Several recent technological developments including advanced neuroimaging and the breeding of new rodent models of white matter injury have provided growing insight into initial damage and repair after a stroke or other damaging event.

Content Level » Research

Keywords » encephalopathy - neurodegeneration - stroke - white matter

Related subjects » Neurology - Neuroscience

Table of contents 

Section I:      White Matter and Evaluation


1          White matter: Basic principles of axonal organization and function

Alexander A Velumian and Marina Samoilova


2          Electrophysiology evaluation of white matter injury           

Mingke Song, Anna Woodbury, Shanping Yu


3          CADASIL and animal models     

Francesco Blasi, PharmD, PhD, Anand Viswanathan, MD, PhD Cenk Ayata, MD


4          Neuroimaging of White Matter Injury: A Multimodal Approach to Vascular Disease  

Gary A. Rosenberg, Branko Huisa, Fakhreya Y. Jalal, Yi Yang


5          Diffusion MRI Biomarkers of White Matter Damage in Traumatic Brain Injury

Maria Ly, Samuel Ji, Michael A. Yassa



Section II:     White Matter Injury in Stroke and other CNS Disorders 


6          Mechanisms underlying the selective vulnerability of developing white matter

Paul A. Rosenberg


7          Neonatal experimental white matter injury     

Zhengwei Cai


8          Focal ischemic white matter injury in experimental models          

Robert Fern


9          Global ischemic white matter injury in patients        

Shinichi Nakao, Yan Xu


10        Experimental global ischemia and white matter injury       

Ji Hae Seo, Kazuhide Hayakawa, Nobukazu Miyamoto, Takakuni Maki, Loc-Duyen, Eng H. Lo, Ken Arai


11        White Matter Injury after Experimental Intracerebral Hemorrhage

Kenneth R. Wagner


12        White Matter Repair after Ischemic Injury       

Elif G Sӧzmen, S. Thomas Carmichael


13        White Matter Injury in Subarachnoid Hemorrhage in Humans

Gian Marco De Marchis, MD and Stephan A. Mayer, MD


14        Neurodegenerative diseases and white matter injury in patients            

George Bartzokis, M.D., Po H. Lu, Psy.D


15        Unmyelinated and myelinated axons exhibit differential injury and treatment response following traumatic brain injury

Thomas M. Reeves, Adele E. Doperalski, Linda L. Phillips


16        Age-Dependent Mechanisms Of White Matter Injury After Stroke           

Selva Baltan


17        White matter damage in multiple sclerosis    

María Victoria Sánchez-Gómez, Fernando Pérez-Cerdá, Carlos Matute


Section III:   Pathophysiology of White Matter Injury      


18        Calcium dyshomeostasis in white matter injury

Elena Alberdi, Asier Ruiz, Carlos Matute


19        Inflammation and white matter injury in animal models of ischemic stroke

Lyanne C. Schlichter, Sarah Hutchings, Starlee Lively


20        Oxidative stress in white matter injury  

Hideyuki Yoshioka, Takuma Wakai, Hiroyuki Kinouchi, Pak H Chan


21        Acute Axonal Injury in White Matter Stroke    

Jason D. Hinman, S. Thomas Carmichael


Section IV     Other white matter injuries      


22        Mitochondria disorder and white matter injury         

R. Anne Stetler, PhD, Rehana K. Leak, PhD, Zheng Jing, PhD, Xiaoming Hu, PhD, Yanqin Gao, MD, Guodong Cao, PhD, and Jun Chen, MD


23        Heave metal and white matter injury    

Yang V. Li


24        Anesthesia and white matter injury

Phillip Vlisides, Zhongcong Xie

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