Logo - springer
Slogan - springer

Biomedical Sciences - Neuroscience | Prions and Diseases

Prions and Diseases

Zou, Wen-Quan, Gambetti, Pierluigi (Eds.)

2013, 670 p. 74 illus., 54 illus. in color. 2 volume-set.

Hardcover
Information

Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

(net) price for USA

ISBN 978-1-4614-5343-7

free shipping for individuals worldwide

online orders shipping within 2-3 days.


add to marked items

$339.00
  • Authored by a team of leading researchers and clinicians
  • Updated knowledge and concepts on pathogenic prion proteins and prion diseases
  • Present state-of the art findings and hypotheses beyond prions and prion diseases
Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases. As a result, the book contains by far the most authoritative views about the past, present, and future of prions and prion diseases.

Content Level » Research

Keywords » disease - neuropathology - pathophysiology - physiology - prion - protein

Related subjects » Animal Sciences - Biochemistry & Biophysics - Human Physiology - Neurology - Neuroscience

Popular Content within this publication 

 

Articles

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Neurosciences.