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  • © 2012

Methylmercury and Neurotoxicity

  • Updated overview on the toxic effects of MeHg on the nervous system
  • Special focus on neurodevelopmental aspects
  • Covers the available data from epidemiological studies as well as the most recent experimental research performed in different animal species
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Neurotoxicity (Current Topics Neurotoxicity, volume 2)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xi
  2. Epidemiological Evidence on Methylmercury Neurotoxicity

    • Jordi Julvez, Takashi Yorifuji, Anna L. Choi, Philippe Grandjean
    Pages 13-35
  3. The Impact of Prenatal Exposure to Methylmercury and Maternal Nutritional Status on Child Development: Findings from the Seychelles Child Development Study

    • Edwin van Wijngaarden, Gary J. Myers, Conrad F. Shamlaye, J. J. Strain, Philip W. Davidson
    Pages 37-53
  4. Methylmercury and Fish Nutrients in Experimental Models

    • M. Christopher Newland
    Pages 55-90
  5. Mercury-Dependent Inhibition of Selenoenzymes and Mercury Toxicity

    • Nicholas V. C. Ralston, Alexander Azenkeng, Laura J. Raymond
    Pages 91-99
  6. Redox State in Mediating Methylmercury Neurotoxicity

    • Marcelo Farina, Michael Aschner, João B. T. Rocha
    Pages 101-125
  7. Behavioural Effects of Exposure to Methylmercury During Early Development

    • Natalia Onishchenko, Stefan Spulber, Sandra Ceccatelli
    Pages 163-198
  8. Epigenetics of Environmental Contaminants

    • Natalia Onishchenko, Nina N. Karpova, Eero Castrén
    Pages 199-218
  9. Methylmercury Neurotoxicity: A Synopsis of In Vitro Effects

    • Lucio G. Costa, Gennaro Giordano
    Pages 219-227
  10. Effects of Methylmercury on Cellular Signal Transduction Systems

    • Fusako Usuki, Masatake Fujimura
    Pages 229-240
  11. Methylmercury Neurotoxicity: Why Are some Cells more Vulnerable than Others?

    • Parvinder Kaur, Michael Aschner, Tore Syversen
    Pages 241-258
  12. Methylmercury and Glia Cells

    • Yin Zhaobao, Marcelo Farina, João B. T. Rocha, Parvinder Kaur, Tore Syversen, Michael Aschner
    Pages 271-285
  13. Methylmercury and Neural Stem Cells

    • Karin Edoff, Sandra Ceccatelli
    Pages 287-302
  14. Zebrafish as a Model for Methylmercury Neurotoxicity

    • Daniel N. Weber, Rebekah H. Klingler, Michael J. Carvan III
    Pages 335-355

About this book

Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHg’s accumulation in fish. Latest US statistics indicate that 46 States have fish consumption advisories. In addition, Hg is a common pollutant in hazardous waste sites, with an estimated 3-4 million children living within one mile of at least one of the 1,300+ active hazardous waste sites in the US. The effects on intellectual function in children prenatally exposed to MeHg via maternal fish consumption have been the subject of two on-going major, prospective, longitudinal studies in the Seychelles and the Faroe Islands. It is important to recognize that the risk for MeHg exposure is not limited only to islanders with high fish consumption.

 

This book will provide state-of-the-art information to the graduate student training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the reader up to date on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies.

Editors and Affiliations

  • , Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

    Sandra Ceccatelli

  • , Department of Pediatrics, Vanderbilt University Medical Center, Nashville, USA

    Michael Aschner

Bibliographic Information

  • Book Title: Methylmercury and Neurotoxicity

  • Editors: Sandra Ceccatelli, Michael Aschner

  • Series Title: Current Topics in Neurotoxicity

  • DOI: https://doi.org/10.1007/978-1-4614-2383-6

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012

  • Hardcover ISBN: 978-1-4614-2382-9Published: 23 March 2012

  • Softcover ISBN: 978-1-4899-9336-6Published: 13 April 2014

  • eBook ISBN: 978-1-4614-2383-6Published: 23 March 2012

  • Series ISSN: 2363-9563

  • Series E-ISSN: 2363-9571

  • Edition Number: 1

  • Number of Pages: XII, 376

  • Topics: Neurochemistry, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access