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  • © 2012

Computational Neuroscience of Drug Addiction

  • Intrigued by the apparent irrational behavior of drug addicts, researchers from a wide range of scientific disciplines have formulated a plethora of theoretical schemes over the years to understand addiction
  • Collects several recent mathematical and neurocomputational models of drug self-administration and addiction
  • Illustrates how mathematical modeling can contribute to our understanding of the mechanisms underlying the transition between the different stages of addiction
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Series in Computational Neuroscience (NEUROSCI, volume 10)

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-XIV
  2. Pharmacological-Based Models of Addiction

    1. Front Matter

      Pages 1-1
  3. Pharmacological-based models of addiction

    1. Control Theory and Addictive Behavior

      • David B. Newlin, Phillip A. Regalia, Thomas I. Seidman, Georgiy Bobashev
      Pages 57-108
  4. Neurocomputational Models of Addiction

    1. Front Matter

      Pages 109-109
  5. Neurocomputational models of addiction

    1. Dual-System Learning Models and Drugs of Abuse

      • Dylan A. Simon, Nathaniel D. Daw
      Pages 145-161
    2. Modeling Decision-Making Systems in Addiction

      • Zeb Kurth-Nelson, A. David Redish
      Pages 163-187
  6. Economic-Based Models of Addiction

    1. Front Matter

      Pages 235-235
  7. Economic-based models of addiction

    1. Policies and Priors

      • Karl Friston
      Pages 237-283
    2. Toward a Computationally Unified Behavioral-Economic Model of Addiction

      • E. Terry Mueller, Laurence P. Carter, Warren K. Bickel
      Pages 285-312
    3. Simulating Patterns of Heroin Addiction Within the Social Context of a Local Heroin Market

      • Lee Hoffer, Georgiy Bobashev, Robert J. Morris
      Pages 313-331
  8. Back Matter

    Pages 333-341

About this book

Drug addiction remains one of the most important public health problems in western societies and is a rising concern for developing nations. Over the past 3 decades, experimental research on the neurobiology and psychology of drug addiction has generated a torrent of exciting data, from the molecular up to the behavioral levels. As a result, a new and pressing challenge for addiction research is to formulate a synthetic theoretical framework that goes well beyond mere scientific eclectism to deepen our understanding of drug addiction and to foster our capacity to prevent and to cure drug addiction. Intrigued by the apparent irrational behavior of drug addicts, researchers from a wide range of scientific disciplines have formulated a plethora of theoretical schemes over the years to understand addiction. However, most of these theories and models are qualitative in nature and are formulated using terms that are often ill-defined. As a result, the empirical validity of these models has been difficult to test rigorously, which has served to generate more controversy than clarity. In this context, as in other scientific fields, mathematical and computational modeling should contribute to the development of more testable and rigorous models of addiction.

Reviews

From the reviews:

“This is a fascinating … new book covering mathematical modeling of various aspects of addiction. … Written and edited by experts in the field, this is a welcome addition to the neuroscientific literature of addictions. … Each chapter concludes with timely and relevant citations of the scientific literature. … This new … book is a stimulating introduction to the field for those with the computational neuroscientific background knowledge to comprehend it.” (Michael Joel Schrift, Doody's Book Reviews, March, 2013)

Editors and Affiliations

  • DEC-ENS, Paris, France

    Boris Gutkin

  • CNRS UMR 5541, Lab.Neuropsychobiologie des, Univ.de Bordeaux, Bordeaux, France

    Serge H. Ahmed

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access