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Biomedical Sciences - Neuroscience | Cochlear Mechanics - Introduction to a Time Domain Analysis of the Nonlinear Cochlea

Cochlear Mechanics

Introduction to a Time Domain Analysis of the Nonlinear Cochlea

Duifhuis, Hendrikus

2012, XIV, 262 p.

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  • Addresses and explains basic differences between linear and nonlinear cochleae
  • Provides a well-justified mathematical approach, with lucid examples
  • Useful to both researchers in auditory neuroscience and students of biophysics and biomedical engineering

The field of cochlear mechanics has received increasing interest over the last few decades. In the majority of these studies, researchers use linear systems analysis or linear approximations of the nonlinear (NL) systems. Even though it has been clear that the intact cochlea operates nonlinearly, lack of tools for proper nonlinear analysis, and widely available tools for linear analysis still lead to inefficient and possibly incorrect interpretation of the biophysics of the cochlea. An example is the presumption that a change in cochlear stiffness at hair cell level must account for the observed change in tuning (or frequency mapping) due to prestin application. Hypotheses like this need to be addressed in a tutorial that is lucid enough to analyze and explain basic differences.

Cochlear Mechanics presents a useful and mathematically justified/justifiable approach in the main part of the text, an approach that will be elucidated with clear examples. The book will be useful to scientists in auditory neuroscience, as well as graduate students in biophysics/biomedical engineering.

Content Level » Research

Related subjects » Biomedical Engineering - Biophysics & Biological Physics - Neuroscience - Otorhinolaryngology

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