Overview
- Editors:
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E. Antonio Chiocca
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Molecular Neuro-Oncology, Neurosurgical Service, Massachussetts General Hospital, Harvard Medical School, Boston, USA
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Xandra O. Breakefield
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Neurogenetics Unit, Massachussetts General Hospital, Harvard Medical Center, Boston, USA
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Table of contents (21 chapters)
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Vectors and Promoters
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- Susanna Chiocca, Matt Cotten
Pages 39-52
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- Cornel Fraefel, Xandra O. Breakefield, David R. Jacoby
Pages 63-82
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- Frances I. Smith, Thomas J. McCown
Pages 83-92
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- Jean-Michel H. Vos, Keith B. Quattrocchi, Brian J. Wendelburg
Pages 93-112
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- Didier Trono, Ulrike Blömer, Luigi Naldini
Pages 113-120
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- Jason G. Smith, Stephen L. Eck
Pages 147-157
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Neuro-Oncology
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Front Matter
Pages 159-159
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- Stephen B. Tatter, Griffith R. Harsh IV
Pages 161-189
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- Candelaria Gomez-Manzano, Juan Fueyo, Athanassios P. Kyritsis, W. K. Alfred Yung
Pages 205-229
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- John H. Sampson, Darell D. Bigner, Glenn Dranoff
Pages 231-294
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- Leslie L. Muldoon, Robert A. Kroll, Michael A. Pagel, Simon Roman-Goldstein, Edward A. Neuwelt
Pages 295-312
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- Rolf F. Barth, Melvin L. Moeschberger
Pages 313-337
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Neurological Diseases
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Front Matter
Pages 339-343
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- Marie-Claude Senut, Isabelle Aubert, Philip J. Horner, Fred H. Gage
Pages 345-375
About this book
Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders.
Reviews
"a very interesting book. . .all 'gene therapy laboratories' and 'neuo-gene therapy laboratories' will be able to derive much intellectual nourishment and stimulation, practical tips, and predictions about the future from this truly challenging volume."-Human Genetics
Editors and Affiliations
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Molecular Neuro-Oncology, Neurosurgical Service, Massachussetts General Hospital, Harvard Medical School, Boston, USA
E. Antonio Chiocca
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Neurogenetics Unit, Massachussetts General Hospital, Harvard Medical Center, Boston, USA
Xandra O. Breakefield