Explores schizophrenia from a neurochemical perspective
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Useful for basic neuroscientists and clinicians alike
This volume of the Handbook of Neurochemistry and Molecular Neurobiology focuses on neurochemical aspects of schizophrenia. Chapters cover the full range of schizophrenia symptoms and anatomical pathologies from neurochemical and molecular biology perspectives. Topics include changes in neurotransmitter systems, alteration in receptors, neurotransmitter release, genetic factors, protein alterations, and redox dysregulation.
Hippocampus.- Redox dysregulation in schizophrenia: Genetic susceptibility and pathophysiological mechanisms.- An overview and current perspective on family studies of schizophrenia.- Synaptic vesicle associated proteins and schizophrenia.- Cortical dopamine in schizophrenia.- G72/g30 in neuropsychiatric disorders.- Cholinergic mechanisms in schizophrenia.- The neurobiology of negative symptoms and the deficit syndrome.- Alterations of neurotransmitter receptors in schizophrenia: Evidence from postmortem studies.- Auditory cortex anatomy and asymmetry in schizophrenia.- Event related potentials (ERPS) in the study of schizophrenia: How pre-clinical ERP studies have contributed to our understanding of schizophrenia.- Neuregulin 1 and schizophrenia.- The role of prefrontal abnormalities in schizophrenia.- Early-stage visual processing deficits in schizophrenia and implications for higher level function.- Magnetic resonance spectroscopy.- Dysbindin-1 and its protein family.- Glutamate and schizophrenia: Phencyclidine, n-methyl-d-aspartate (NMDA) receptors: Etiology and treatment.