Overview
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Table of contents (21 entries)
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Front Matter
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Neuro-Endocrine Immunoregulation
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The Brain's Immune System
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Neuro Immune Mechanisms ofBrain Diseases
About this book
This volume contains data on multiple immunomodulators, many of which are also the products of hypothalamic brain cell neurosecretion. Interleukins (IL-1a, IL-1ß, IL-2, IL-4, IL-6, TNFa), immunophylin and ubiquitin as well as proline rich peptides, comprised of 10-15 amino acids are being produced in N. Supraopticus and N. Paraventricularis and then secreted into neurohypophysis. Along the neurosecretion of the mentioned cytokines, there are other immunomodulators, the primary structure of which had been completely deciphered such as: Immunophyllins, intracellular receptors of immunosuppressors FK506, cyclosporine A., rapamicin. They are peptidyl-prolyl-cis-trans-isomerases. There are novel immunological hypothalamic factors such as ubiquitin, macrophage migration inhibitory factor (MIF), as well as Thymosin ß 4(1-39). This data allowed us to propose the concept of neuroendocrine immune system of the brain.
Reviews
From the reviews of the third edition:
"A new edition of the Handbook of Neurochemistry and Molecular Neurobiology has now been issued in 25 volumes. It contains fundamental data on current molecular neurobiology, neuroimmunology, and neuropathology. This is the first time that the series contain Neuroimmunology, which summarizes achievements in neurochemistry, neuroendocrinology, neurophysiology, and the pathology of the nervous system. … This book presents research performed by scientists in various countries. … a handbook for scientists, students, and clinicians." (K. G. Gevorgyan, Neurochemical Journal, Vol. 3 (1), 2009)
Editors and Affiliations
Bibliographic Information
Book Title: Handbook of Neurochemistry and Molecular Neurobiology
Book Subtitle: Neuroimmunology
Editors: Abel Lajtha, Armen Galoyan, Hugo O. Besedovsky
DOI: https://doi.org/10.1007/978-0-387-30398-7
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Reference Module Biomedical and Life Sciences
Copyright Information: Springer-Verlag US 2008
Hardcover ISBN: 978-0-387-30358-1Published: 14 December 2007
eBook ISBN: 978-0-387-30398-7Published: 18 February 2010
Edition Number: 3
Number of Pages: XIII, 495
Topics: Neurosciences