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Biomedical Sciences - Molecular Medicine | Store-operated Ca2+ entry (SOCE) pathways - Emerging signaling concepts in human (patho)physiology

Store-operated Ca2+ entry (SOCE) pathways

Emerging signaling concepts in human (patho)physiology

Groschner, Klaus, Graier, Wolfgang, Romanin, Christoph (Eds.)

2012, XXII, 482 p. With online files/update.

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  • Provides insight into the recent advances that emerged in the field Comprehensive and elaborate overview on a timely topic of cellular signaling
  • Shows clear and concise illustrations that outline the key scientific concepts of SOCE Reviews critically the mechanistic hypthesis and novel therapeutic concepts of SOCE Provides an interdisciplinary approach
  • Combines basic research with clinical aspects
Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.

Content Level » Research

Keywords » Calcium Entry - Calcium Signaling - ORAI Pathway - STIM Pathway - Transient Receptor Potential TRP

Related subjects » Biophysics & Biological Physics - Cardiology & Angiology - Cell Biology - Human Physiology - Molecular Medicine

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