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Biomedical Sciences - Molecular Medicine | Molecular Aspects of Hematologic Malignancies - Diagnostic Tools and Clinical Applications

Molecular Aspects of Hematologic Malignancies

Diagnostic Tools and Clinical Applications

Witt, Michal, Dawidowska, Malgorzata, Szczepanski, Tomasz (Eds.)

2012, X, 476 p. 45 illus., 23 illus. in color.

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  • Up-to-date information on the molecular basis of selected hematologic disorders
  • Practical reference for molecular laboratory procedures
  • Of interest to clinical oncologists and hematologists as well as to graduates in molecular medicine, human genetics and laboratory medicine

This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.

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Content Level » Research

Keywords » hematology - leukemia - minimal residual disease - molecular biology - oncology - stem cell transplantation

Related subjects » Biomedical Sciences - Cancer Research - Human Genetics - Internal Medicine - Molecular Medicine

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