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Biophysics of RNA Folding

  • Book
  • © 2013

Overview

Editors:
  1. Rick Russell

    1. , Dept. of Chemistry and Biochemistry, University of Texas, Austin, USA

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  • Focuses on concepts and methods relating to developments in study of RNA folding
  • Unique approach integrates methods and topics, rather than having an initial series of chapters focused solely on methods
  • Comprehensive and up-to-date survey of biophysical approaches to the dynamic field of RNA biology
  • Includes supplementary material: sn.pub/extras

Part of the book series: Biophysics for the Life Sciences (BIOPHYS, volume 3)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-vi
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  2. Introduction and Overview

    • Rick Russell
    Pages 1-10

  3. Comparative Analysis of the Higher-Order Structure of RNA

    • Robin R. Gutell
    Pages 11-22

  4. Graph Applications to RNA Structure and Function

    • Namhee Kim, Katherine Niccole Fuhr, Tamar Schlick
    Pages 23-51

  5. Prediction and Coarse-Grained Modeling of RNA Structures

    • Zhen Xia, Pengyu Ren
    Pages 53-68

  6. Studying RNA Folding Using Site-Directed Spin Labeling

    • Xiaojun Zhang, Peter Z. Qin
    Pages 69-87

  7. The RNA Recognition Motif and Messenger RNA

    • Kathleen B. Hall
    Pages 89-116

  8. Memory Effects in RNA Folding Dynamics Revealed by Single-Molecule Fluorescence

    • Rui Zhao, David Rueda
    Pages 117-133

  9. An Integrated Picture of HDV Ribozyme Catalysis

    • Barbara L. Golden, Sharon Hammes-Schiffer, Paul R. Carey, Philip C. Bevilacqua
    Pages 135-167

  10. Combining Biochemical and Structural Information to Model RNA-Protein Complex Assembly

    • Maithili Saoji, Chun Geng, Paul J. Paukstelis
    Pages 169-186

  11. Following RNA Folding From Local and Global Perspectives

    • Michael Brenowitz, Lois Pollack
    Pages 187-203

  12. The Roles of Chaperones in RNA Folding

    • Pilar Tijerina, Rick Russell
    Pages 205-230

  13. Back Matter

    Pages 231-236
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About this book

This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, viral RNAs, and self-splicing introns. In addition to the fundamental features of RNA folding, the central experimental and computational approaches in the field are presented with an emphasis on their individual strengths and limitations, and how they can be combined to be more powerful than any method alone; these approaches include NMR, single molecule fluorescence, site-directed spin labeling, structure mapping, comparative sequence analysis, graph theory, course-grained 3D modeling, and more. This volume will be of interest to professional researchers and advanced students entering the field of RNA folding.

Editors and Affiliations

  • , Dept. of Chemistry and Biochemistry, University of Texas, Austin, USA

    Rick Russell

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