2015, Approx. 360 p. 172 illus., 68 illus. in color.
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Introduces novel interdisciplinary research where conventional biorheology is extended to the nano- and micro scale
Covers cutting-edge research of the structure and function of biomaterials at the molecular level
Provides step-by-step explanations of methods, with examples of clinical applications
Integrating basic to applied science and technology in medicine, pharmaceutics, molecular biology, biomedical engineering, biophysics, and irreversible thermodynamics, this book covers cutting-edge research of the structure and function of biomaterials at a molecular level. In addition, it examines for the first time studies performed at the nano- and microscale. With innovative technologies and methodologies aiming to clarify the molecular mechanism and macroscopic relationship, Nano/Micro Science and Technology in Biorheology thoroughly covers the basic principles of these studies, with helpful step-by-step explanations of methodologies and insight into medical applications. Written by pioneering researchers, the book is a valuable resource for academics and industry scientists, as well as graduate students, working or studying in bio-related fields.
Chapter 1. Introduction and theoretical background Chapter 2. Rheological aspect of conformational change and molecular aggregation of macromolecules Chapter 3. Amyloid fibrils observed under elongated flow field Chapter 4. Irreversible Structure Transformation of Complex Molecular Bilayer by Means of Rheo-DWS (Diffusion Wave Spectroscopy) Chapter 5. Diffusion and thermal diffusion of biomolecules by DLS and laser holography Chapter 6. Diffusion of water in materials by PGSE-NMR (Pulse Gradient Field Spin-Echo method) Chapter 7. Nuclear Magnetic Elastography and its Application to Diagnosis Chapter 8. Dynamics and glass transition of water, proteins, and polymer in aqueous solutions by dielectric relaxation spectroscopy Chapter 9. Dynamics of glass transition of water in foods and proteins by dielectric relaxation spectroscopy Chapter 10. Rheological analysis of blood coagulation process by means of dielectric relaxation Chapter 11. Rheological Aspect of Preparation and Biological Functions of Nano/Microcapsules Chapter 12. Biomedical application of soft nano/micro particles Chapter 13. Control of Multi-Scale Structure of Scaffolds and its Application to Tissue Engineering Chapter 14. Sensing of Biomolecules and Cells by Semiconductor Device Chapter 15. Imaging of single DNA chain16. AFM imaging of cells