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Biomedical Sciences - Medical Microbiology | Molecular Parasitology - Genomes, Proteomes, Glycomes and Lipidomes

Molecular Parasitology

Genomes, Proteomes, Glycomes and Lipidomes

Walochnik, Julia, Duchêne, Michael (Eds.)

2015, Approx. 400 p. 60 illus. in color.

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  • About this book

  • Gives a condensed overview to the state of knowledge in molecular parasitology​
  • Refers to 'the molecules' relevant in parasitology: genomes, proteomes, glycomes, lipidomes
  • Clearly structured and well arranged
In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets? This book intends to give an overview of the state of knowledge on “the molecules” of parasites – on their genomes, proteomes, glycomes and lipidomes. ​

Content Level » Research

Related subjects » Medical Microbiology

Table of contents 

List of Contributors.- Preface.- Abbreviations.- Introduction.- The Molecules.- Genomics.- Nuclear Genomes.- Mitochondrial Genomes.- Plastid Genomes.- Proteomics.- Cysteine Proteases.- Metalloproteases.- Glycomics.- N-Glycans.- O-Glycans.- The Parasites.- Protozoa.- Giardia.- Trichomonas.- Naegleria.- Trypanosoma.- Leishmania.- Cryptosporidium.- Toxoplasma.- Plasmodium.- Acanthamoeba.- Entamoeba.- Helminths.- Schistosoma.- Taeniids.- Echinococcus.- Ascaris.- Toxocara.- Strongyloids.- Filariasis.- Arthropods.- Ticks.- Insects.- Hot Topics.- Phylogeny.- Comparison of Genomes of Anaerobic Protozoa.- Evolution.- The Apicomplexans.- Sex in Leishmania and Trypanosoma?.- Host-Parasite Interactions.- Antigens and Antibodies.- Epigenetics.- Drug Design.- Kinetoplastids.- Filarias and Wolbachias.- Vaccine Development.- Malaria.- Leishmaniasis.- Further Reading per Chapter.- Citations.- Index.​

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