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  • © 2011

Giardia

A Model Organism

  • Comprehensive volume on Giardia biology and pathogenesis as well as clinical treatment.

  • Molecular biology aspects are described in detail.

  • Separate section for experimental methods in Giardia research

  • Internationally prestigious authors, designated experts in the field

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Table of contents (26 chapters)

  1. Front Matter

    Pages I-XIV
  2. Taxonomy and Epidemiology of Giardia

    1. Front Matter

      Pages 1-1
    2. Epidemiology of Giardiasis in Humans

      • Simone M. Cacciò, Hein Sprong
      Pages 17-28
  3. Taxonomy and Epidemiology of Giardia

    1. Taxonomy of Giardia Species

      • R. C. Andrew Thompson, Paul T. Monis
      Pages 3-15
    2. Waterborne and Environmentally-Borne Giardiasis

      • Lucy J. Robertson, Yvonne Ai Lian Lim
      Pages 29-69
  4. Molecular Biology of Giardia

    1. Front Matter

      Pages 93-93
    2. Genomics of Giardia

      • Hilary G. Morrison, Staffan Svärd
      Pages 95-101
    3. The Glycoproteins of Giardia

      • John Samuelson, Phillips W. Robbins
      Pages 103-110
    4. Mass Spectrometric Analysis of Phospholipids and Fatty Acids in Giardia lamblia

      • Mayte Yichoy, Ernesto S. Nakayasu, Atasi De Chatterjee, Stephen B. Aley, Igor C. Almeida, Siddhartha Das
      Pages 111-125
    5. Giardia Metabolism

      • Edward L. Jarroll, Harry van Keulen, Timothy A. Paget, Donald G. Lindmark
      Pages 127-137
  5. Cellular Biology of Giardia

    1. Front Matter

      Pages 139-139
    2. The Ultrastructure of Giardia During Growth and Differentiation

      • Marlene Benchimol, Wanderley De Souza
      Pages 141-160
    3. The Giardia Mitosomes

      • Jan Tachezy, Pavel Doležal
      Pages 185-200
    4. Signaling Pathways in Giardia lamblia

      • Tineke Lauwaet, Frances D. Gillin
      Pages 201-209
    5. Transcription and Recombination in Giardia

      • Rodney D. Adam
      Pages 211-218
    6. Post-transcriptional Gene Silencing and Translation in Giardia

      • Pablo R. Gargantini, César G. Prucca, Hugo D. Luján
      Pages 233-244
    7. Antigenic Variation in Giardia

      • Theodore E. Nash
      Pages 245-257
  6. Cellular Biology of Giardia

    1. Cell Cycle Regulation and Cell Division in Giardia

      • Scott C. Dawson, Eva Nohýnková, Michael Cipriano
      Pages 161-183
    2. Intracellular Protein Trafficking

      • Adrian B. Hehl
      Pages 219-231

About this book

Giardia is a relatively simple eukaryotic microbe, causing acute and chronic diarrhea which has been used as a model to understand complex biological processes occurring in eukaryotic cells. Further, due to its parasitic lifestyle, Giardia is an excellent system for the study of the mechanisms of adaptation and cell differentiation from the perspectives of molecular and cell biology. This book presents a comprehensive review of the current state of knowledge regarding all aspects of Giardia’s biology, including epidemiology, cell and molecular biology, genetics, pathogenesis, diagnostics, and clinical treatment. It was written by internationally renowned authors, the leading researchers in the field including several chapters with techniques and resources available for the study of this microorganism. Questions that need to be addressed to fully understand the molecular mechanisms of the parasite as well as the cause of its pathology are presented. Furthermore, Giardia’s biology is compared with that of other parasites in relation to their complexity. This volume is an indispensable resource for researchers working with this parasite. It is a “must” for libraries and the bookshelves of everyone interested in the biology of parasites and early-branching eukaryotes.

Editors and Affiliations

  • Laboratory of Biochemistry and Molecular Biology, School of Medicine, Catholic University of Córdoba, Córdoba, Argentina

    Hugo D. Luján

  • Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

    Staffan Svärd

About the editors

Dr. Luján received his Ph.D. in biochemistry from the School of Chemistry, National University of Córdoba, Argentina, in 1991. Until 1996 he performed postdoctoral work in the United States at the National Institute of Allergy and Infectious Diseases, National Institutes of Health. He is a full professor of biochemistry and cell biology in the School of Medicine, Catholic University of Córdoba, Argentina. He also is an independent investigator at the National Council for Science and Technology of Argentina. Dr. Svärd received his PhD in Microbiology at Uppsala University, Uppsala, Sweden in 1995. He performed postdoctoral work in United States at UCSD, San Diego followed by six years at the Karolinska Institute, Stockholm, Sweden. Currently he is a professor of Eukaryotic Microbiology at Uppsala University.

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access