Maresca, Bruno, Kobayashi, George S., Yamaguchi, Hideyo (Eds.)
Softcover reprint of the original 1st ed. 1993, XIV, 257 pp. 90 figs., 21 tabs.
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Presented here are recent achievements in molecular biology
of non-pathogenic yeast and filamenous fungi as well as of
human pathogens. Thebook is diveded into 4 sections:
- Molecular Biology of Yeast;
- Molecular Biology of Filamenous Fungi;
- New Tools and Prospectives for Medical Mycology;
- Fungal Morphogenesis.
It focuses on aspects of medical mycology, namely isolation
of specific genes and strategies for developing new targets
for antifungal therapy.
Molecular Biology of Yeast.- Cell Cycle Regulation in Fission Yeast.- Yeast Genes Overcoming Growth Arrest Induced by 1,10-Phenanthroline.- Reverse Genetics in a Non-Conventional Yeast, Candida maltosa.- The Complement C3D-Binding Receptor (CR2) of Candida albicans: Cloning and Sequence Analysis of a Gene Fragment Homologous with a Human CR2 cDNA Clone.- Biology, Physiology, Biochemistry and Molecular Genetics of Trichosporon Yeasts.- Physiological Functions of Vacuoles in Yeast: Mechanism of Sequestration of Metabolites and Proteins into Vacuoles.- Characterization of a Candida albicans-Specific DNA Fragment.- Recent Advances in the Molecular Biology of Cryptococcus neoformans.- Molecular Biology of Kluyveromyces lactis.- Gene Regulatory Circuits in S. cerevisiae as a Tool for the Identification of Heterologous Eukaryotic Regulatory Elements.- Molecular Biology of Filamentous Fungi.- Molecular Breeding in Filamentous Fungi with Emphasis on Aspergilli.- TubB ?-Tubulin is Essential for Sexual Development in Aspergillus nidulans.- The Heat Shock Response of Neurospora crassa.- Blue Light Regulated Expression of Geranylgeranyl Pyrophosphate Synthetase (Albino-3) Gene in Neurospora crassa.- Expression of Genes for the Biosynthesis of Penicillin.- New Tools and Prospectives for Medical Mycology.- Imaging of the Yeast Killer Phenomenon.- cDNA Cloning of Candida albicans Aspartic Proteinase and Its Diagnostic Application.- Molecular Biotyping of Candida in Experimental and Clinical Studies.- Homoserine Dehydrogenase as a Selective Target Molecule for Antifungal Action.- Molecular Mechanisms of Antifungal Activity and Fungal Resistence: Focus on Inhibitors of Ergosterol Biosynthesis.- Molecular Studies on Azole Sensitivity in Fungi.- Antifungal Chemotherapy and Drug Strategies: Projected Clinical Needs.- Funding Medical Mycology: Strategies for Attracting the Private Sector.- Fungal Morphogenesis.- Chromosomal Organization of Histoplasma capsulation.- Chitin, Chitin Synthase and Chitin Synthase Conserved Region Homologues in Wangiella dermatitidis.- Heat Shock Response and Adaptation during Morphogenesis in Histoplasma capsulatum.