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  • © 2015

Human and Mosquito Lysozymes

Old Molecules for New Approaches Against Malaria

Editors:

  • Covers groundbreaking research into new understandings and uses for older and well-known enzymes
  • Explores both human and mosquito lysozymes and their medical potential
  • Considers the potential role of other antimicrobial peptides, ie TEP-1 in the mosquito, and PF-4 in the human host
  • Includes supplementary material: sn.pub/extras

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-ix
  2. Etiopathogenesis and Pathophysiology of Malaria

    • Giuliana Giribaldi, Sarah D’Alessandro, Mauro Prato, Nicoletta Basilico
    Pages 1-18
  3. Malaria Diagnosis, Therapy, Vaccines, and Vector Control

    • Nicoletta Basilico, Roberta Spaccapelo, Sarah D’Alessandro
    Pages 19-43
  4. Lysozymes in the Animal Kingdom

    • Vivian Tullio, Roberta Spaccapelo, Manuela Polimeni
    Pages 45-57
  5. Role of Lysozymes of Anopheles Mosquitoes in Plasmodium Development

    • Clelia Oliva, Luca Facchinelli, Nicoletta Basilico, Roberta Spaccapelo
    Pages 59-65
  6. Effects of Malaria Products on Human Monocyte and Neutrophil Degranulation and Lysozyme Release

    • Manuela Polimeni, Giuliana Giribaldi, Mauro Prato
    Pages 67-81
  7. Human Lysozyme in Malaria Patients: Possible Role as Biomarker for Disease Severity

    • Mauro Prato, Manuela Polimeni, Vivian Tullio
    Pages 83-90
  8. Beyond Lysozyme: Antimicrobial Peptides Against Malaria

    • Sarah D’Alessandro, Vivian Tullio, Giuliana Giribaldi
    Pages 91-101
  9. Back Matter

    Pages 103-108

About this book

Malaria remains an alarming emergency in developing countries. It is thus urgent to identify any parasite or host molecules that can serve as new affordable markers for early diagnosis of disease complications or as new targets for vector control. In this context, human and mosquito lysozymes are good candidate molecules, as their involvement in malaria has been recently reported by several independent groups. This book reviews the grounded knowledge on malaria etiology and physiopathology, as well as the current approaches for diagnosis, therapy, and vector control. In addition, the emerging evidence on the involvement of human and mosquito lysozymes in malaria from available experimental models and clinical studies is thoroughly discussed, as is the potential use of other antimicrobial peptides against malaria. Intriguingly, the contributors propose that old well-known molecules such as lysozymes might be used as new targets for cost-effective strategies to fight malaria.

Editors and Affiliations

  • Neuroscience, University of Torino, Torino, Italy

    Mauro Prato

About the editor

Mauro Prato currently works as an Adjunct Professor of Biochemistry at the University of Torino, Italy. His research activity focuses on the involvement of proteolytic enzymes in malaria. His track-record includes 40 papers published by peer-reviewed journals, 1 book, 7 book chapters, 97 communications in well-established conferences, and 1 patent.

Bibliographic Information

  • Book Title: Human and Mosquito Lysozymes

  • Book Subtitle: Old Molecules for New Approaches Against Malaria

  • Editors: Mauro Prato

  • DOI: https://doi.org/10.1007/978-3-319-09432-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-09431-1Published: 04 November 2014

  • Softcover ISBN: 978-3-319-38089-6Published: 23 August 2016

  • eBook ISBN: 978-3-319-09432-8Published: 16 October 2014

  • Edition Number: 1

  • Number of Pages: IX, 108

  • Number of Illustrations: 5 b/w illustrations, 16 illustrations in colour

  • Topics: Parasitology, Medical Microbiology, Immunology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access