Logo - springer
Slogan - springer

Biomedical Sciences - Immunology | Antimicrobial Peptides and Innate Immunity

Antimicrobial Peptides and Innate Immunity

Hiemstra, Pieter S., Zaat, Sebastian A. J. (Eds.)

2013, XI, 384 p. 38 illus., 23 illus. in color.

A product of Springer Basel
Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$159.00

(net) price for USA

ISBN 978-3-0348-0541-4

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase


learn more about Springer eBooks

add to marked items

Hardcover
Information

Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$199.00

(net) price for USA

ISBN 978-3-0348-0540-7

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

  • Provides a comprehensive overview on these endogenous antibiotics
  • Includes information on role in inflammatory diseases and gives an outlook on new therapeutic options
  • Written by experts in the field of antimicrobial/host defense peptide research

Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. This book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic.

The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (including defensins), and the role of these peptides in host defense in plants and micro-organisms. The realization that antimicrobial peptides also display functions distinct from their direct antimicrobial action is the focus of the next chapters, and puts these peptides center stage in immunity and wound repair.  Further chapters discuss the role of antimicrobial peptides in disease, by providing an overview of mechanisms in bacterial resistance to antimicrobial peptides and a discussion of their role in inflammatory bowel disease, cystic fibrosis lung disease and chronic obstructive pulmonary disease. Finally, the book shows how knowledge of the function of antimicrobial peptides and their regulation can be used to design new therapies for inflammatory and infectious disorders. This is a very important area of research because of the increase in resistance of micro-organisms to conventional antibiotics. Therefore the use of synthetic or recombinant peptides, or agents that stimulate the endogenous production of antimicrobial peptides, provides an attractive alternative for conventional antibiotics.

Content Level » Research

Keywords » Antimicrobial peptides - Endogenous antibiotics - Host defense peptides - Host-microbe interaction during infection - Inflammatory and infectious diseases - Innate immunity

Related subjects » Biochemistry & Biophysics - Immunology - Internal Medicine - Medical Microbiology

Table of contents / Preface / Sample pages 

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Immunology.