Overview
- Editors:
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Antonio Giordano
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Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia
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Gaetano Romano
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Department of Neurosurgery, Thomas Jefferson University, Philadelphia
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Table of contents (22 protocols)
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Front Matter
Pages i-xiii
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Analysis of Cyclins and Cyclin-Dependent Kinases
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 23-28
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 29-31
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 33-36
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 37-40
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 41-44
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 45-55
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 57-62
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- Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly S. Harrington, Hayk Hovhannisyan et al.
Pages 63-67
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- Henry Hoff, Hong Zhang, Christian Sell
Pages 79-92
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Analysis of the Factors Involved in Cell Cycle Deregulation
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- Henry Hoff, Barbara Belletti, Hong Zhang, Christian Sell
Pages 95-104
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- Martyn K. White, Caterina Cinti
Pages 105-111
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- Carmela Trimarchi, Dario La Sala, Alessandra Zamparelli, Caterina Cinti
Pages 113-118
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Cellular Response to Deoxyribonucleic Acid Damage
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Front Matter
Pages 119-119
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- Salvatore Cortellino, David P. Turner, Domenico Albino, Alfonso Bellacosa
Pages 121-125
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- Salvatore Cortellino, David P. Turner, Alfonso Bellacosa
Pages 127-132
About this book
Cell Cycle Control and Dysregulation Protocols focuses on emerging methodologies for studying the cell cycle, kinases, and kinase inhibitors. It addresses the issue of gene expression in vivo and in vitro, the analysis of cyclin-dependent kinase inhibitors, protein degradation mediated by the proteosome, the analysis of the transformed cell phenotype, and innovative techniques to detect apoptosis. Because there are already many manuals and protocols available, along with commercial kits and reagents, a variety of the more common techniques have not been included in our book. The protocols described, based on rather sophisticated techniques for in vivo and in vitro studies, consist of molecular biology, biochemistry, and various types of immunoassays. Indeed, the authors have successfully accomplished an arduous task by presenting several topics in the simplest possible manner. We are confident that Cell Cycle Control and Dysregulation Protocols will facilitate and optimize the work of practical scientists involved in researching the cell cycle. We greatly acknowledge the extraordinary contribution of the authors in writing this book.
Reviews
"State-of-the-art and highly practical...offers pathbreaking researchers powerful tools for probing the cell cycle regulation across a wide variety of pathologies." - Tumori
Editors and Affiliations
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Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia
Antonio Giordano
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Department of Neurosurgery, Thomas Jefferson University, Philadelphia
Gaetano Romano
