Immunotherapy for Infectious Diseases

1. Front Matter

   Pages i-x

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2. Basic Principles of Immunity

   1. Front Matter

      Pages 1-1

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   2. Humoral Immunity

      • Peter L. Nara

      Pages 3-22

   3. Some Basic Cellular Immunology Principles Applied to the Pathogenesis of Infectious Diseases

      • R. Pat Bucy, Paul Goepfert

      Pages 23-38

   4. Immune Defense at Mucosal Surfaces

      • Prosper N. Boyaka, Jerry R. McGhee

      Pages 39-60

3. Molecular Basis for Immunotherapy

   1. Front Matter

      Pages 61-61

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   2. Production of Immunoglobulins and Monoclonal Antibodies Targeting Infectious Diseases

      • Renate Kunert, Hermann Katinger

      Pages 63-97

   3. Dendritic Cells

      • Smriti K. Kundu-Raychaudhuri, Edgar G. Engleman

      Pages 99-116

   4. Cytokines, Cytokine Antagonists, and Growth Factors for Treating Infections

      • Barbara G. Matthews

      Pages 117-128

   5. Principles of Vaccine Development

      • Constantin A. Bona

      Pages 129-147

4. Immunotherapy for HIV Infection

   1. Front Matter

      Pages 149-149

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   2. Immunopathogenesis of HIV Infection

      • Lawrence M. Fox

      Pages 151-161

   3. Immune Reconstitution with Antiretroviral Chemotherapy

      • Elizabeth Connick

      Pages 163-179

   4. Active Immunization as Therapy for HIV Infection

      • Spyros A. Kalams

      Pages 181-197

   5. Passive Immunotherapy for HIV Infection

      • Jeffrey M. Jacobson

      Pages 199-220

   6. Host Cell-Directed Approaches for Treating HIV and Restoring Immune Function

      • J. Michael Kilby, R. Pat Bucy

      Pages 221-236

   7. Gene Therapy for HIV-1 Infection

      • Ralph Dornburg, Roger J. Pomerantz

      Pages 237-248

5. Immunotherapy for Infectious Diseases Other than HIV

   1. Front Matter

      Pages 249-249

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   2. Immunotherapy of Viral Infections Other than HIV

      • Michelle Onorato, Richard B. Pollard

      Pages 251-258

   3. Immunotherapy for Virus-Associated Malignancies

      • Uluhan Sili, Helen Heslop, Cliona M. Rooney

      Pages 259-274

In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers HIV-specific passive and active immunization strategies, gene therapy, and host cell-targeted approaches for treating HIV infection and restoring immune function.

• Antigen
• HIV
• HIV infection
• Sepsis
• bacteria
• bacterial infection
• bacterial infections
• fungal infection
• gene therapy
• infection
• infections
• infectious
• infectious disease
• infectious diseases
• viral infection

"This book is extemely well-organiaed, and while it conains alot of new information, it is easy to read due to its presentation. Thus, while each chapter could stand alone, the way in which the information is integrated enhances its clarity as the format melds the old information with the new. Finally, the topic is timely and comprehensive." -Doody's Health Sciences Book Review Journal

• AIDS Center, Mount Sinai School of Medicine, New York, USA

  Jeffrey M. Jacobson

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