The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence
Embers, Monica E. (Ed.)
2012, XVI, 268 p.
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Explores the spirochetes ability to survive in a healthy host
Addresses the various kinds of spirochetes
Studies both direct and indirect suppression of immune signals
This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites. It also explores antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.