Crossroads between Innate and Adaptive Immunity

1. Front Matter

   Pages i-xx

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2. Signal Transduction in DC Differentiation: Winged Messengers and Achilles’ Heel

   • Inna Lindner, Pedro J. Cejas, Louise M. Carlson, Julie Torruellas, Gregory V. Plano, Kelvin P. Lee

   Pages 1-29

3. Shaping Naive and Memory Cd8+ T Cell Responses in Pathogen Infections Through Antigen Presentation

   • Gabrielle T. Belz, Nicholas S. Wilson, Fiona Kupresanin, Adele M. Mount, Christopher M. Smith

   Pages 31-42

4. Understanding the Role of Innate Immunity in the Mechanism of Action of the Live Attenuated Yellow Fever Vaccine 17D

   • Troy D. Querec, Bali Pulendran

   Pages 43-53

5. The Function of Local Lymphoid Tissues in Pulmonary Immune Responses

   • Juan Moyron-Quiroz, Javier Rangel-Moreno, Damian M. Carragher, Troy D. Randall

   Pages 55-68

6. The Yin and Yang of Adaptive Immunity in Allogeneic Hematopoietic Cell Transplantation: Donor Antigen-Presenting Cells Can Either Augment or Inhibit Donor T Cell Alloreactivity

   • Jian-Ming Li, Edmund K. Waller

   Pages 69-87

7. It’s Only Innate Immunity But I Like it

   • Emanuela Marcenaro, Mariella Della Chiesa, Alessandra Dondero, Bruna Ferranti, Alessandro Moretta

   Pages 89-101

8. Innate Tumor Immune Surveillance

   • Mark J. Smyth, Jeremy Swann, Yoshihiro Hayakawa

   Pages 103-111

9. Regulation of Adaptive Immunity by Cells of the Innate Immune System: Bone Marrow Natural Killer Cells Inhibit T Cell Proliferation

   • Prachi P. Trivedi, Taba K. Amouzegar, Paul C. Roberts, Norbert A. Wolf, Robert H. Swanborg

   Pages 113-120

10. Induction and Maintenance of Cd8+ T Cells Specific for Persistent Viruses

    • Ester M. M. van Leeuwen, Ineke J. M. ten Berge, René A. W. van Lier

    Pages 121-137

11. Germinal Center-Derived B Cell Memory

    • Craig P. Chappell, Joshy Jacob

    Pages 139-148

12. CD28 and Cd27 Costimulation of Cd8+ T Cells: A Story of Survival

    • Douglas V. Dolfi, Peter D. Katsikis

    Pages 149-170

13. CD38: An Ecto-Enzyme at the Crossroads of Innate and Adaptive Immune Responses

    • Santiago Partidá-Sánchez, Laura Rivero-Nava, Guixiu Shi, Frances E. Lund

    Pages 171-183

14. Vascular Leukocytes: a Population with Angiogenic and Immunossuppressive Properties Highly Represented in Ovarian Cancer

    • George Coukos, Jose R. Conejo-Garcia, Ron Buckanovich, Fabian Benencia

    Pages 185-193

15. CD4+ T Cells Cooperate With Macrophages for Specific Elimination of MHC Class II-Negative Cancer Cells

    • Alexandre Corthay

    Pages 195-208

16. Receptors and Pathways in Innate Antifungal Immunity

    • Teresa Zelante, Claudia Montagnoli, Silvia Bozza, Roberta Gaziano, Silvia Bellocchio, Pierluigi Bonifazi et al.

    Pages 209-221

17. Back Matter

    Pages 223-232

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This compilation presents minireviews derived from work presented at the - gean Conference: “First Crossroads between Innate and Adaptive Immunity,” which occurred October 9–14, 2005 at the Hilton Conference Center on the - land of Rhodes, Greece. The conference included sessions dedicated to host r- ognition of and response to pathogens, innate immune networks, antigen pres- tation, and adaptive immune responses, each headlined by a leading scientist at the forefront of that field. The intimate networking and interaction of dendritic cells, T cells, B cells, NK cells, NK-T cells, and complement during the host response to pathogens and tumors are only now starting to be elucidated. The respective fields that focus on these immune cells and molecules tend to exist in parallel worlds, with minimum exchange of information and ideas. The goal of this conference was to initiate crosstalk between these immunological fields, and to promote and facilitate discussion on the interactions between the innate - mune response and the adaptive immune response, and ultimately breed colla- ration between these areas of study. The “First Crossroads between Innate and Adaptive Immunity” Aegean Conference succeeded in bringing together and connecting scientists and experts from around the world to address critical areas of innate and adaptive immunity — something necessary for the development of more efficient scientific exchange and crosspollination between these fields.

• Antigen
• infection
• infections
• transplantation
• vaccine
• virus
• infectious diseases

• Drexel University College of Medicine, Philadelphia, USA

  Peter D. Katsikis

• La Jolla Institute for Allergy and Immunology, La Jolla, USA

  Stephen P. Schoenberger

• Emory Vaccine Center, Emory University, Atlanta, USA

  Bali Pulendran

Policies and ethics