Cellular Physiology and Metabolism of Physical Exercise

1. Front Matter

   Pages I-XVI

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2. Human Evolution and Physical Exercise: The Concept of Being “Born to Run”

   • Livio Luzi

   Pages 1-7

3. Cell Morphology and Function: The Specificities of Muscle Cells

   • Anna Maestroni

   Pages 9-15

4. The Cell Membrane of the Contractile Unit

   • Gianpaolo Zerbini

   Pages 17-21

5. Gene Polymorphisms and Athletic Performance

   • Ileana Terruzzi

   Pages 23-31

6. Nutrients and Whole-Body Energy Metabolism: The Impact of Physical Exercise

   • Stefano Benedini

   Pages 33-42

7. Mitochondrial and Non-mitochondrial Studies of ATP Synthesis

   • Roberto Codella

   Pages 43-53

8. Excessive Nutrients and Regional Energy Metabolism

   • Gianluca Perseghin

   Pages 55-66

9. Muscle Biopsy To Investigate Mitochondrial Turnover

   • Rocco Barazzoni

   Pages 67-84

10. Introduction to the Tracer-Based Study of Metabolism In Vivo

    • Andrea Caumo, Livio Luzi

    Pages 85-97

11. Physical Activity and Inflammation

    • Raffaele Di Fenza, Paolo Fiorina

    Pages 99-108

12. The HPA Axis and the Regulation of Energy Balance

    • Francesca Frigerio

    Pages 109-121

13. Physical Exercise in Obesity and Anorexia Nervosa

    • Alberto Battezzati, Simona Bertoli

    Pages 123-131

14. Physical Exercise and Transplantation

    • Valentina Delmonte, Vincenzo Lauriola, Rodolfo Alejandro, Camillo Ricordi

    Pages 133-145

15. The Baboon as a Primate Model To Study the Physiology and Metabolic Effects of Exercise

    • Francesca Casiraghi, Alberto Omar Chavez, Nicholas Musi, Franco Folli

    Pages 147-161

16. Back Matter

    Pages 163-164

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The book covers areas of cellular physiology and metabolism that are of interest to scientists involved in research in diabetes and metabolic diseases. Some chapters of the book are specifically research-oriented, as all the authors are actively practicing either bench or clinical research in the area. Nonetheless, since the work is fully comprehensive of the discipline, it is also suitable for university classes of graduate and undergraduate students. In particular, the book discusses classical aspects of cellular physiology and the metabolism of physical exercise, as well as novel topics like exercise in transplantation and exercise in beta-cell failure, which mark the frontiers of research in sport-related sciences and research. Exercise physiologists, biologists and physicians are the specific professional and academic targets of this work. The team of authors together with the editor are world-renowned experts in the field of physiology and metabolism applied to sport sciences.

• Metabolism
• Muscle cells
• Physical exercise
• Sport and eating disorders
• diabetes
• Metabolomics

• Department of Sport Sciences, Nutrition and Health, University of Milan, Milan, Italy

  Livio Luzi

Livio Luzi MD is Professor of Endocrinology and a world renowned diabetologist. In addition to his current role as Dean of the Faculty of Exercise Sciences at the University of Milan Medical School, he is also Adjunct Professor at the Diabetes Research Institute, Miami FL, USA. He has published over 300 scientific papers in the area of diabetes/metabolism/physical exercise and over the past 30 years has trained and/or supervised more than 30 fellows. Several of these have gone on to become principal investigators in the area of diabetes/metabolism/physical exercise. The two authors are presently working in the United States (Ricordi, University of Miami and Fiorina, Harvard University) and are top scientists in their field of research. Most of the remaining authors work in Milan and are world renowned scientists in their respective fields of research.

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