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Biomedical Sciences - Human Physiology | Gasotransmitters: Physiology and Pathophysiology

Gasotransmitters: Physiology and Pathophysiology

Hermann, Anton, Sitdikova, Guzel F., Weiger, Thomas M. (Eds.)

2012, X, 206 p.

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  • Reviews the biological, pharmacological and medical functions of the signalling molecules nitric oxide, carbon monoxide, and hydrogen sulfide
  • Written by experts
  • Richly illustrated

Since the epochal discovery of the radical and highly toxic gas nitric oxide (NO) as a signaling molecule, two other no less toxic gases – carbon monoxide (CO) and hydrogen sulfide (H2S) – have been found to also be involved in a plethora of physiological and pathophysiological functions. The gases termed gasotransmitters play an increasingly important role in understanding how signalling into and between cells is modulated and fine-tuned. The advent of gasotransmitters has profoundly changed our way of thinking about biosynthesis, liberation, storage and action mechanisms in cellular signaling. In recent years an impressive amount of new data, distributed throughout the existing literature, has been generated. For this book the editors have recruited distinguished colleagues in the field to summarize and review important biological, pharmacological and medical functions and their implications, as well as methods for the detection of gasotransmitters.

Content Level » Research

Keywords » BK channels - carbon monoxide - gasotransmitter - hydrogen sulfide - nitric oxide - signaling molecules

Related subjects » Biochemistry & Biophysics - Cell Biology - Human Physiology - Neuroscience

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