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  • Book
  • © 2012

Stress Challenges and Immunity in Space

From Mechanisms to Monitoring and Preventive Strategies

  • Unique in focussing specifically on stress and immunity in space

  • Goes beyond other publications on the physiological changes during space flight

  • Adopts an interdisciplinary approach to analyze the complex interaction of living conditions in space, the immune system, and astronauts’ health

  • Provides information that may help to prevent, diagnose, and counteract immune-related alterations in health

  • Includes supplementary material: sn.pub/extras

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-xiii
  2. Prelude

    1. Front Matter

      Pages 1-1
    2. Space Travel: An Integrative View from the Scientists of the Topical Team “Stress and Immunity”

      • Sarah Baatout, Alexander Choukèr, Ines Kaufmann, Nicola Montano, Siegfried Praun, Dominique de Quervain et al.
      Pages 5-8
  3. “Stress and Immunity” - Research: A Link Between Space and Earth

    1. Front Matter

      Pages 9-9
  4. Stress & Immunity -research: a link between space and earth

    1. What Is Stress?

      • Bruce S. McEwen, Ilia N. Karatsoreos
      Pages 11-29
    2. The Impact of Everyday Stressors on the Immune System and Health

      • Lisa M. Christian, Ronald Glaser
      Pages 31-43
  5. Stress and Immune Allostasis in Space, from Brain to Immune Responses

    1. Front Matter

      Pages 45-45
  6. Stress & Immune Allostasis in Space, from brain to immune responses

    1. The Autonomic Nervous System

      • Nicola Montano, Eleonora Tobaldini, Alberto Porta
      Pages 71-86
    2. Circadian Rhythm and Stress

      • Mathias Steinach, Hanns-Christian Gunga
      Pages 87-106
    3. Endocannabinoids, “New-Old” Mediators of Stress Homeostasis

      • Daniela Hauer, Roland Toth, Gustav Schelling
      Pages 107-126
    4. Innate Immunity Under Conditions of Space Flight

      • Matthias Feuerecker, Alex P. Salam, Ines Kaufmann, André Martignoni, Alexander Choukèr
      Pages 141-153
    5. NK Cells Assessments: A Thirty-Year-Old History of Immune Stress Interaction in Space

      • Boris Morukov, Marina Rykova, Eugenia Antropova
      Pages 155-164
    6. Adaptive Immunity and Spaceflight

      • Brian Crucian, Clarence Sams
      Pages 165-175
    7. Stress, Hypoxia, and Immune Responses

      • Manfred Thiel, Michail Sitkovsky, Alexander Choukèr
      Pages 177-185
    8. Gravitational Force: Triggered Stress in Cells of the Immune System

      • Oliver Ullrich, Cora S. Thiel
      Pages 187-202
    9. Microbial Stress: Spaceflight-induced Alterations in Microbial Virulence and Infectious Disease Risks for the Crew

      • C. Mark Ott, Aurélie Crabbé, James W. Wilson, Jennifer Barrila, Sarah L. Castro, Cheryl A. Nickerson
      Pages 203-225
    10. Stress, Spaceflight, and Latent Herpes Virus Reactivation

      • Raymond P. Stowe, Duane L. Pierson, Satish K. Mehta
      Pages 227-237

About this book

Stress of either psychological or physical nature can activate and/or paralyse humans’ innate and adaptive immunity.  However, adequate immunity is crucial to the maintenance of health on earth and in space.  During space flight, human physiology and health are challenged by complex environmental stressors which might be at their most pronounced during lunar or interplanetary missions.  While previous publications have addressed the physiological changes that occur during space flight, this book goes further, by adopting an interdisciplinary approach to analyze the complex interaction of living conditions in space, the immune system, and astronauts’ health.  It is explained how such analysis of the consequences of stress for the immune system may help in preventing, diagnosing, and counteracting immune-related alterations in health on earth as well as in space

Editors and Affiliations

  • Klinikum Großhadern, Klinik für Anästhesiologie und, Universitätsklinikum München, München, Germany

    Alexander Chouker

Bibliographic Information

Buy it now

Buying options

eBook USD 179.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 229.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access