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Hypoxia, Metabolic Acidosis, and the Circulation

  • Book
  • © 1992

Overview

Editors:
  1. Allen I. Arieff

    1. Department of Medicine, School of Medicine and Veterans Affairs Medical Center, University of California, San Francisco, USA

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  • Shows how hypoxia and metabolic acidosis affect the heart, lungs, blood vessels and other organs at the cellular level, the tissue level, and finally, at the level of the entire organ
  • Gives an overview of hypoxia and metabolic acidosis treatment
  • Written by experts in the field

Part of the book series: Clinical Physiology (CLINPHY)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-x
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  3. Clinical Manifestations of Hypoxia

    1. Front Matter

      Pages 83-83
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    2. Clinical Implications of the Pathophysiology of Lactic Acidosis: The Role of Defects in Lactate Disposal

      • R. D. Cohen
      Pages 85-98

    3. Acidosis and the Pulmonary Circulation

      • Bryan E. Marshall, Carol Marshall
      Pages 99-115

    4. Pathogenesis of Metabolic Acidosis with Hypoxia

      • Allen I. Arieff
      Pages 116-138

    5. Effects of Sodium Bicarbonate on Myocardial Metabolism and Circulatory Function during Hypoxia

      • Robert M. Bersin
      Pages 139-174

    6. Alkalinizing Agents for the Treatment of Cardiac Arrest

      • Max Harry Weil, Fulvio Kette, Raul J. Gazmuri, Eric C. Rackow
      Pages 175-195

    7. Therapy of Lactic Acidosis: Alternatives to Sodium Bicarbonate

      • Allen I. Arieff
      Pages 196-210

  4. Back Matter

    Pages 211-215
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Keywords

About this book

In recent years, there has been a wealth of new information on the physiological and biochemical consequences of hypoxia, or low blood levels of oxygen. This new volume discusses the implications of these new findings on the pathophysiology, development, and treatment of hypoxic metabolic acidosis. The volume is part of the Clinical Physiology series sponsored by the American Physiological Society, and is based on a FASEB symposium held in May 1988. Hypoxia was once thought to affect organs in a similar manner, but it is now known that each is affected differently. The author shows how hypoxia and metabolic acidosis affect the heart, lungs, blood vessels and other organs at the cellular level, the tissue level, and finally, at the level of the entire organ. The book then proceeds to a description of the situations in which hypoxic metabolic acidosis develops, such as during high altitude exposure, cardiac arrest, and lactic acidosis. The last few chapters give an overview of treatment. Traditional therapy has consisted largely of the intravenous administration of sodium bicarbonate. This method has come under increasing scrutiny however, and the range of problems associated with the use of sodium bicarbonate is examined fully. Newer alternative agents for managing hypoxic acidosis are reviewed as well. This up-to-date review of hypoxia and metabolic acidosis should be of interest to physiologists, internists, cardiologists, chest physicians, anesthesiologists, and intensive care specialists.

Editors and Affiliations

  • Department of Medicine, School of Medicine and Veterans Affairs Medical Center, University of California, San Francisco, USA

    Allen I. Arieff

Bibliographic Information

  • Book Title: Hypoxia, Metabolic Acidosis, and the Circulation

  • Editors: Allen I. Arieff

  • Series Title: Clinical Physiology

  • DOI: https://doi.org/10.1007/978-1-4614-7542-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: American Physiological Society 1992

  • eBook ISBN: 978-1-4614-7542-2Published: 27 May 2013

  • Edition Number: 1

  • Number of Pages: 232

  • Additional Information: Originally Published by Oxford University Press 1992

  • Topics: Human Physiology

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