Gaultier, Claude, Bourbon, Jacques R, Post, Martin (Eds.)
Originally Published by Oxford University Press 1999
1999, 472 p.
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Comprehensive review of the complex series of cellular and molecular interactions required for lung development
Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
Lung Branching Morphogenesis: Role of Growth Factors and Extracellular Matrix.- Development of Lung Elastic Matrix.- Differentiation and Maturation of Airway Epithelial Cells: Role of Extracellular Matrix and Growth Factors.- Gene Expression in Alveolar Development.- Lung Development and Pulmonary Angiogenesis.- Development of the Pulmonary Vasculature.- Nitric Oxide and Endothelin in the Developing Pulmonary Circulation: Physiologic and Clinical Implications.- Development of Cellular Host Defense Mechanisms.- Development of Lung Epithelial Ion Transport: Implications for Neonatal Lung Disease.- Mechanisms of Cell Growth and Tissue Repair.-Bioactive Peptides and Lung Development.- Transgenic Models of Lung Development and Disease.- Nutritional Aspects of Lung Development.- Pulmonary Hypoplasia: Role of Mechanical Factors in Prenatal Lung Growth.- Pulmonary Antioxidant Defense Mechanisms.- Lung Development after Transplantation.