Logo - springer
Slogan - springer

Biomedical Sciences - Human Genetics | Gene Therapy for Autoimmune and Inflammatory Diseases

Gene Therapy for Autoimmune and Inflammatory Diseases

Chernajovsky, Yuti, Robbins, Paul D. (Eds.)

2010, XI, 239 p.

A product of Springer Basel
Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$219.00

(net) price for USA

ISBN 978-3-0346-0165-8

digitally watermarked, no DRM

Included Format: PDF

download immediately after purchase


learn more about Springer eBooks

add to marked items

Hardcover
Information

Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$279.00

(net) price for USA

ISBN 978-3-0346-0164-1

free shipping for individuals worldwide

online orders shipping within 2-3 days.


add to marked items

Softcover
Information

Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$279.00

(net) price for USA

ISBN 978-3-0348-0306-9

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields to review the state of the art advances on topics ranging from disease entities to vectors and engineered cells. The different approaches described in each chapter take into consideration the biomedical knowledge of these diseases and address the complexities of delivering long-term genetic interventions. Gene therapy also serves as a testing ground for new therapeutic entities and helps provide proof of principle for their potential therapeutic role in animal models of disease. Scaling up from mice to men still remains an important h- dle not only from the quantitative point of view, but also for currently unknown and unexpected secondary effects of the vector or the transgene. Some of these approaches have already been tested in the clinic, but much more needs to be done to understand the human conditions treated and the n- ural history of their pathology. We are indebted to the secretarial assistance of Ms. Lin Wells (Bone and Joint Research Unit, London, UK) and the help of Hans Detlef Klüber for his help in getting this book published. We hope this book will be of interest to c- nicians and scientists and inspiring to students of the subject who will use their own ingenuity and knowledge to further forward this discipline into clinical use.

Content Level » Research

Keywords » Arthritis - Autoimmune Diseases - DNA - Immunology - Inflammatory Diseases - Promoter - gene therapy - genes

Related subjects » Human Genetics - Immunology - Molecular Medicine - Pharmacology & Toxicology - Rheumatology

Table of contents 

From the contents: Rheumatoid arthritis.- Crohn's disease/IBD.- Diabetes.- Cystic fibrosis.- Multiple sclerosis.- Myositis.- Osteoarthritis.- Sjögrens syndrome.- Lupus.- New developments in vectors:Regulated promoters.- AAV Vectors.- Plasmid delivery.- Gutted adenovirus.- Cells as carriers of gene therapy including stem cells.- Perspectives for the future developments of gene therapy for autoimmune and inflammatory therapy.

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Gene Therapy.