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Biomedical Sciences - Human Genetics | Stress-Induced Mutagenesis

Stress-Induced Mutagenesis

Mittelman, David (Ed.)

2013, XV, 275 p. 48 illus., 31 illus. in color.

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  • Covers pathways of stress-induced mutagenesis in all systems
  • Serves a wide audience
  • Examines changed ideas about mutation and evolution
The discoveries of stress-induced mutation and epigenetic inheritance have challenged the claim of independence between the evolutionary forces of mutation and selection. In “Stress-Induced Mutagenesis”, leading experts provide the key evidence for and the molecular details of stress-induced genetic and epigenetic mutation, integrating cross-disciplinary observations from a number of species and biological systems, including human. The observations have vast implications for evolutionary biology but also for human medicine. A comprehensive understanding of stress-induced mutagenesis and the processes underlying evolvability, will enable gains in the treatment and management of cancer, as well as other human disorders that result from damaged or unstable genomes.

Content Level » Research

Related subjects » Biochemistry & Biophysics - Biomedical Sciences - Human Genetics

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