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Biomedical Sciences - Human Genetics | Epigenetics of Aging

Epigenetics of Aging

Tollefsbol, Trygve O. (Ed.)

2010, XIX, 469 p.

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  • Intended for those with interests ranging from the fundamental basis of aging to interventions in slowing the aging process or treating age-related diseases
  • Covers epigenetics as it relates to aging and age-related diseases, a relatively new field that is showing considerable promise in revolutionizing how the aging process is viewed
  • Provides coverage of not only established aspects of epigenetics and aging, but also new approaches and perceptions in this important area of research

Revealing the molecular basis of aging has been one of the most challenging aspects of medical science, and now the epigenetics of aging is in a Renaissance phase. This seminal work covers the fascinating role of epigenetics in aging, ranging from basic epigenetic processes of aging to epigenetic drugs that may intervene in allow aging and age-related diseases.

Epigenetics of Aging presents in-depth analyses of DNA methylation, histone modifications, RNA alterations, and chromosomal defects that impact the aging process. It also includes detailed essays describing the impact of epigenetics on aging, the epigenetics of age-related diseases, and future directions and perspectives on the epigenetics of aging.

With chapters authored by leading researchers in the field, this seminal book on the epigenetics of aging:

-Ranges from basic science to clinical practice

-Describes the importance of epigenetics in numerous diseases of aging such as cancer, Alzheimer’s disease, immune defects, and osteoporosis

-Includes the role of epigenetics in premature aging diseases such as progeria

-Highlights emerging aspects of epigenetics in aging, such as polycomb group genes and noncoding RNAs

-Covers sirtuins, chromatin alterations, and the role of epigenetic drift in aging

-Describes the impact of the environment and diet in modulating epigenetic processes during aging

Epigenetics of Aging is the first book in this exponentially expanding field, and will be an indispensable source of information for those with interests in epigenetics and/or aging. This authoritative core textbook for advanced students or medical scientists and practitioners details the fascinating and revolutionary field of the epigenetics of aging and covers the most recent advances that impact the longevity of living organisms.

Content Level » Research

Keywords » Chromosom - DNA - Telomere - aging - genetics - senescence

Related subjects » Cancer Research - Human Genetics - Pharmacology & Toxicology

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