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Biomedical Sciences - Human Genetics | DNA Repair and Human Disease

DNA Repair and Human Disease

Balajee, Adayabalam

2006, XII, 150 p.

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  • About this book

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

Content Level » Research

Keywords » DNA - DNA repair - Telomere - Xeroderma pigmentosum - aging - alzheimer's disease - cancer - cell - cell cycle - protein

Related subjects » Cell Biology - Human Genetics - Medical Microbiology

Table of contents / Sample pages 

Human Premature Aging Disorders and Dysfunction of DNA Repair.- DNA Repair Aspects for RecQ Helicase Disorders.- Trichothiodystrophy.- Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair.- Radiosensitivity of Cells Derived from Down Syndrome Patients.- The Fanconi Anemia/BRCA Pathway.- Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators?.- Mechanisms of DNA Damage and Repair in Alzheimer Disease.- Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells.- Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients.

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