Biomarkers in Cardiovascular Disease

1. Front Matter

   Pages i-xxix

   PDF

2. General Aspects

   1. Front Matter

      Pages 1-1

      PDF

   2. Testing Pharmacological Profiles with Biomarkers Relevant to Cardiovascular Profiles

      • Giuseppe Derosa, Pamela Maffioli

      Pages 3-26

   3. Use of Multiple Biomarkers to Estimate Cardiovascular Drug Efficacy: Advantage of a PRE Score

      • Paul A. Smink, Hiddo L. J. Heerspink

      Pages 27-38

   4. Cardiovascular Disease Biomarkers in Clinical Use and Their Modulation by Functional Foods

      • Arpita Basu, Stacy Morris, Paramita Basu, Timothy J. Lyons

      Pages 39-62

   5. Biomarker-Guided Therapy for Chronic Heart Failure

      • Alexander E. Berezin

      Pages 63-83

3. Circulating and Body Fluid Biomarkers

   1. Front Matter

      Pages 85-85

      PDF

   2. Biomarkers of the Extracellular Matrix and of Collagen Fragments

      • Georgios K. Chalikias, Dimitrios N. Tziakas

      Pages 87-124

   3. PCSK9 as a Biomarker of Cardiovascular Disease

      • Teik Chye Ooi, Hussein Abujrad

      Pages 125-151

   4. Circulating Vasoactive Peptide Urotensin II and Relationships with Cardiovascular Disease

      • Isabella Albanese, Adel Schwertani

      Pages 153-175

   5. Association of Fetuin-A with Carotid Intima-Media Thickness and Vascular Diseases

      • Aydın Akyüz

      Pages 177-196

   6. Serum Cholinesterase Activities as Biomarkers of Cardiac Malfunctioning

      • Nir Waiskopf, Shani Shenhar-Tsarfaty, Hermona Soreq

      Pages 197-218

   7. Triglycerides (TG) to High-Density Lipoprotein (HDL-c) Ratio (TG/HDL-c Ratio) as a Marker of Cardiometabolic Risk

      • Tommaso de Giorgis, Angelika Mohn

      Pages 219-234

   8. Biomarkers of Myocardial Cell Damage: Heart-Type Fatty Acid Binding Protein (H-FABP) for the Early Evaluation of Suspected Acute Coronary Syndrome

      • Robert T. A. Willemsen, Geert Jan Dinant, Jan F. C. Glatz

      Pages 235-265

   9. Uncarboxylated Matrix Gla Protein as a Biomarker in Cardiovascular Disease: Applications for Research and for Routine Diagnostics

      • Cees Vermeer, Nadja E. A. Drummen, Marjo H. J. Knapen, Fokko J. Zandbergen

      Pages 267-283

   10. MicroRNA-133: Biomarker and Mediator of Cardiovascular Diseases

       • J. Francisco Nistal, Ana V. Villar, Raquel García, María A. Hurlé

       Pages 285-317

   11. Troponin Elevation Beyond Coronary Arteries

       • Manolis Vavuranakis, Maria Kariori, Theodore G. Papaioannou, Dimitrios Tousoulis

       Pages 319-340

   12. Circulating Vascular Endothelial Growth Factor-1 in Cardiovascular Disease

       • Alexander E. Berezin

       Pages 341-357

   13. Macrophage Metalloprotease (MMP)-12 as a Cardiovascular Biomarker

       • Flavia Del Porto, Noemi Cifani, Livia Ferri, Maria Proietta, Luigi Tritapepe, Cira di Gioia et al.

       Pages 359-379

   14. Homocysteine as a Biomarker in Vascular Disease

       • Pilar Codoñer-Franch, Eulalia Alonso-Iglesias

       Pages 381-406

On an annual basis, over 17 million people die due to cardiovascular disease. This represents a third of all global deaths. The World Health Organisation have identified cardiovascular disease as the leading cause of death worldwide.  Although many cardiovascular conditions are preventable, there is a need for accurate characterisation and diagnosis of cardiovascular conditions before, during and after treatments. Much of this characterisation entails the use of biological indicators, i.e biomarkers. Biomarkers in Cardiovascular Disease combines detailed information on different cardiovascular conditions and the concomitant application of conventional, new and emerging biomarkers. It covers the latest knowledge, trends and applications. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.

• Application to prognosis
• Biomarkers in disease
• Cancer Research
• Discovery of biomarkers
• High throughput technologies

• Department of Biomedical Science, Faculty of Science & Technology , University of Westminster, London, United Kingdom

  Vinood B. Patel

• Department of Nutrition and Dietetics, Division of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom

  Victor R. Preedy

Professor Victor R. Preedy is a senior faculty member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1993 he gained his second doctoral degree, for his outstanding contribution to protein metabolism in health and disease. He has received membership and fellowship of a number of academic and professional bodies in the UK, including the Royal College of Pathologists, the Royal Institute of Public Health, and the Royal Society of Chemistry. Professor Preedy has published over 570 articles, which includes 165 peer-reviewed manuscripts based on original research, 100 reviews, and over 50 books and book volumes.

Policies and ethics