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  • © 2017

Biomarkers in Liver Disease

  • Embraces a holistic approach to different conditions that affect the liver and the use of biomarkers
  • Updates scientists and professionals on advances across the disciplines
  • Discusses potential applications of the latest knowledge and innovations
  • Identifies key facts and defines words and terms for the lay person
  • Opens the field to the all readers inquiring into this important area of research
  • Includes supplementary material: sn.pub/extras

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Table of contents (46 entries)

  1. Front Matter

    Pages i-xxvii
  2. General Aspects and Introductory Material

    1. Front Matter

      Pages 1-1
    2. Traditional Markers in Liver Disease

      • Giuseppe Derosa, Pamela Maffioli
      Pages 3-22
    3. Hepascore and Its Application to Liver Disease

      • Yi Huang, Gary P. Jeffrey, Leon A. Adams
      Pages 23-45
    4. Model for End-Stage Liver Disease (MELD) Score as a Biomarker

      • Deepika Devuni, Jawad Ahmad
      Pages 47-70
    5. Mechanistic Biomarkers in Liver Diseases

      • Mitchell R. McGill, Benjamin L. Woolbright, James L. Weemhoff, Hartmut Jaeschke
      Pages 71-97
    6. Liver Transplantation Biomarkers in the Metabolomics Era

      • Miriam Cortes, Juan Carlos García-Cañaveras, Eugenia Pareja, Agustín Lahoz
      Pages 99-128
    7. Liver Biomarkers and Their Applications to Nutritional Interventions in Animal Studies

      • Cynthia Aparecida de Castro, Manoela Maciel dos Santos Dias, Karina Ana da Silva, Sandra Aparecida dos Reis, Lisiane Lopes da Conceição, Letícia De Nadai Marcon et al.
      Pages 129-152
    8. Serum Biomarkers for Evaluating Portal Hypertension

      • Saad Elias, Barhoum Masad, Assy Nimer
      Pages 153-166
    9. Biomarkers for Recurrence of Hepatocellular Carcinoma

      • Seow Chong Lee, Hwee Tong Tan, Maxey Ching Ming Chung
      Pages 167-191
    10. Biomarkers to Monitor Graft Function Following Liver Transplantation

      • Cornelia J. Verhoeven, Luc J. W. van der Laan, Jeroen de Jonge, Herold J. Metselaar
      Pages 193-220
    11. Biomarkers of Extracellular Matrix Remodeling in Liver Diseases

      • Mette J. Nielsen, Diana J. Leeming, Morten A. Karsdal, Aleksander Krag
      Pages 221-246
  3. Body Fluids, Tissue, and Specific Biomarkers

    1. Front Matter

      Pages 265-265
    2. Biomarkers in Focus: Alanine Aminotransferase

      • Guido Engelmann
      Pages 267-280
    3. Bilirubin as a Biomarker in Liver Disease

      • Nahum Méndez-Sánchez, Libor Vítek, Nancy E. Aguilar-Olivos, Misael Uribe
      Pages 281-304
    4. AST-to-Platelet Ratio Index (APRI) as Marker in Liver Disease

      • Agnieszka Bakula, Maciej Dadalski
      Pages 305-320
    5. Soluble CD163 (sCD163): Biomarker of Kupffer Cell Activation in Liver Disease

      • Holger Jon Møller, Konstantin Kazankov, Sidsel Rødgaard-Hansen, Marlene Christina Nielsen, Thomas D. Sandahl, Hendrik Vilstrup et al.
      Pages 321-348
    6. CD133 and EpCAM as Biomarkers in Liver Diseases

      • Anthony W. H. Chan, Ka-Fai To
      Pages 349-372
    7. Graft-Derived Cell-Free DNA as a Biomarker in Liver Transplantation

      • Michael Oellerich, Ekkehard Schütz, Julia Beck, Otto Kollmar, Philipp Kanzow, Anna Blum et al.
      Pages 373-386

About this book

There are numerous types of liver disease that may be due to toxic agents (such as alcohol or drugs), infectious agents including viruses, congenital conditions and even poor dietary patterns. It has been suggested that there are over 100 different types.  As the consequences of liver failure can be devastating it is important that appropriate diagnosis and monitoring is carried out. Much of this characterisation entails the use of biological indicators, i.e biomarkers. Biomarkers in Liver Disease embraces a holistic approach by combining detailed information on different conditions that affect the liver and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge, trends and innovations. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.

Editors and Affiliations

  • Department of Biomedical Science, Faculty of Science and Technology, University of Westminster, London, United Kingdom

    Vinood B. Patel

  • Diabetes and Nutritional Sciences Research Division, Faculty of Life Science and Medicine, King’s College London, London, United Kingdom

    Victor R. Preedy

About the editors

Professor Victor R. Preedy is a senior faculty member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1993 he gained his second doctoral degree, for his outstanding contribution to protein metabolism in health and disease. He has received membership and fellowship of a number of academic and professional bodies in the UK, including the Royal College of Pathologists, the Royal Institute of Public Health, and the Royal Society of Chemistry. Professor Preedy has published over 570 articles, which includes 165 peer-reviewed manuscripts based on original research, 100 reviews, and over 50 books and book volumes.

Bibliographic Information

Buy it now

Buying options

eBook USD 449.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access