Logo - springer
Slogan - springer

Biomedical Sciences - Cancer Research | Stem Cells and Cancer Stem Cells, Volume 10 - Therapeutic Applications in Disease and Injury

Stem Cells and Cancer Stem Cells, Volume 10

Therapeutic Applications in Disease and Injury

Hayat, M.A. (Ed.)

2013, XLII, 298 p. 35 illus., 28 illus. in color.

Available Formats:

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.


(net) price for USA

ISBN 978-94-007-6262-6

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase

learn more about Springer eBooks

add to marked items


Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.


(net) price for USA

ISBN 978-94-007-6261-9

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days

add to marked items

  • Presents state-of-the art papers on research into stem cells and cancer stem cells, and the uses of stem cells to treat disease and regenerate tissue
  • Includes the work of 66 expert contributors representing 13 countries
  • Assesses current understanding of stem cells and cancer stem cells, and stimulates future research

Presenting contributions by 66 experts representing 13 countries, Volume 10 of the series Stem Cells and Cancer Stem Cells synthesizes current understanding of the causes, diagnosis, and therapy of major human diseases and debilitating tissue and organ injuries, using cell-based treatment. This volume presents contemporary research into generation, preservation, and uses of stem cells in fighting disease and tissue/organ injuries.

The contents of the volume are organized into five sections. Mesenchymal Stem Cells section includes chapters on the use of stem cells in bone regeneration, studies and trials of stem cells in autoimmune diseases, and differences between adipose tissue-derived mesenchymal stem cells and bone marrow-derived mesenchymal stem cells as regulators of immune response. Induced Pluripotent Stem Cells section offers chapters on drug discovery using human IPSC-based disease models, and on generation of antigen-specific  lymphocytes from IPSCs. Neural Cells and Neural Stem Cells section discusses use of bacterial artificial chromosomes in the genetic identification of stem cell-derived neural cell types, and use of moderate low temperature to preserve the stemness of neural stem cells. The section, Role of Stem Cells in Disease, discusses stem cell support in high-dose chemotherapy of Non-Hodgkin’s Lymphomas; potential targets for drug resistant leukemic stem cells, bone marrow stem cell therapies for diabetes mellitus. This section also discusses the use of stem cells in treating thyroid, breast and bone cancers, hempophilia and Parkinson’s Disease. The section, Stem Cell Transplantation, includes chapters on reducing fungal infection in allogenic stem cell transplantation patients, use of Bulsufan/Fludarabine for conditioning in haematopoietic stem cell transplantation, and interleukin-7 receptor alpha polymorphisms in allogeneic stem cell transplantation.

The editor, M.A. Hayat, is a Distinguished Professor in the Department of Biological Sciences at Kean University, Union, New Jersey, USA.

Content Level » Professional/practitioner

Keywords » Induced Pluripotent Stem Cells (IPSC) - Mesenchymal Stem Cells - Neural Stem Cells - Stem Cell Transplantation - Tissue Regeneration

Related subjects » Cancer Research - Medicine - Oncology & Hematology

Table of contents 


I Mesenchymal stem cells

1. Mesenchymal stem cells in bone regeneration

2. Experimental (preclinical) studies and clinical trials of adipose tissue-derived mesenchymal stem cells for Autoimmune diseases

3. Validity of markers for epithelial cells and mesenchymal Cells

4. Mesenchymal stem cell survival in infarcted myocardium: adhesion and anti-death signals

 5. Hepatogenic differentiation: comparison between adipose tissue -derived stem cells and bone marrow mesenchymal stem cells

6. Fibrin for encapsulation of human mesenchymal stem cells for chondrogenic differentiation.

7. Differences between adipose tissue-derived mesenchymal  stem cells and bone marrow-derived mesenchymal stem cells as regulators of the immune response

8. Transforming growth factor-beta induced chrondrogenic differentiation of bone marrow-derived mesenchymal stem cells: role of smad signaling pathways


II Induced pluripotent stem cells

9. Drug discovery using human ipsc based disease models and functional hepatic cells

10. Generation of antigen-specific t lymphocytes from induced pluripotent stem cells for adoptive immunotherapy


III Neural cells and neural stem cells

11. Genetic identification of human embryonic stem cell-derived neural cell types using bacterial artificial chromosomes

12. Moderate low temperature preserves the stemness of neural stem cells (methods)


IV Role of stem cells in disease

 13. High-dose chemotherapy with autologous stem cell support in the treatment of transformed b-cell non-hodgkin's lymphomas

14. The wnt/β-catenin pathway as a potential target for drug Resistant leukemic stem cells

15. Bone marrow stem cell therapies for diabetes mellitus and its complications

16.thyroid cancer stem cells – strategies for therapeutic targeting

17. Role of cancer stem cell in mammary carcinogenesis and its clinical implication

18. Critical analysis of parkinson’s disease models and cell-based therapy

19. Presence of an early lineage stem cell phenotype in meningioma-initiating cells

20. Isolation and characterization of cancer stem cells from dog glioblastoma

21. Role of stem cell niche in the development of bone metastases (an update)

22. Treatment of hemophilia a using b cell-directed protein delivery


V Stem cell transplantation

23. Reduction in the risk invasive fungal infection relapse in patients undergoing allogenic stem cell transplantation              using caspofunginas secondary prophylaxis

24. Hematopoietic stem cell transplantation in elderly patients with myelodisplastic syndrome and acute myelogenous leukemia: use of busulfan/fludarabine for conditioning

25. Co-transplantation of islets with mesenychymal stem cells improves islet revascularization and reversal of hyperglycemia

26. Significance of interleukin -7 receptor alpha polymorphisms in allogeneic stem cell transplantation


Popular Content within this publication 



Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Cancer Research.