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Tumors of the Central Nervous System, Volume 8

Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma

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  • © 2012

Overview

Editors:
  1. M.A. Hayat

    1. , Kean University, Room 213, Library building, Union, USA

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  • New technologies and their applications in tumor diagnosis, treatment, and prognosis are discussed
  • Methods to assess the effectiveness of cancer treatments are presented
  • The importance of the quality of life after cancer therapy is pointed out
  • Molecular profiling of brain tumors to select targeted therapy in clinical trials is explained
  • A large number of color figures are included

Part of the book series: Tumors of the Central Nervous System (TCNS, volume 8)

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-xxxvii
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  2. Astrocytoma

    1. Front Matter

      Pages 1-1
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    2. Astrocytoma Cell Line: Role of Brain Natriuretic Peptide

      • Tomohiro Osanai, Chisato Katoh, Ken Okumura
      Pages 3-11

    3. Malignant Brain Astrocytomas: Extent of Resection Affects Survival

      • Kaisorn L. Chaichana, Matthew J. McGirt
      Pages 13-20

  3. Medulloblastoma

    1. Front Matter

      Pages 21-21
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    2. Medulloblastoma: Classification (A Review)

      • Valentina Caracciolo, Antonio Giordano
      Pages 23-33

    3. Medulloblastomas: Clinically Important MicroRNA Genes

      • Deepak Kamnasaran
      Pages 35-46

    4. Medulloblastoma: Role of OTX2 Transcription Factors

      • Austin Mattox, Jing Li, Chunhui Di, D. Cory Adamson
      Pages 47-58

    5. Molecular Mechanisms of Chemoresistance in Medulloblastoma

      • Violaine Sée, Barry Pizer, Daniel Meley
      Pages 59-69

    6. Extraneural Metastasis in Medulloblastoma

      • Arnold C. Paulino
      Pages 71-75

    7. Medulloblastoma: Therapy with Bortezomib/Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

      • Ronald Koschny, Peter Ahnert, Heidrun Holland
      Pages 77-83

    8. Standard-Risk Medulloblastoma: Hyperfractionated Radiotherapy

      • Christian Carrie, Marie-Pierre Sunyach
      Pages 85-90

  4. Retinoblastoma

    1. Front Matter

      Pages 91-91
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    2. Retinoma and Retinoblastoma: Genomic Hybridisation

      • Mariangela Amenduni, Gabriella Livide, Francesca Ariani, Alessandra Renieri
      Pages 93-102

    3. Cell Cycle Control by Ataxia Telangiectasia Mutated Protein Through Regulating Retinoblastoma Protein Phosphorylation

      • Javier G. Pizarro, Antoni Camins, Felix Junyent, Ester Verdaguer, Carme Auladell, Carlos Beas-Zarate et al.
      Pages 103-115

    4. Role of Survivin in Retinoblastoma: Diagnosis and Prognosis

      • Hanan Shehata, Azza Abou Ghalia, Eman Elsayed
      Pages 117-124

    5. Retinoblastoma Epigenetics

      • Domenico Mastrangelo, Cosimo Loré, Giovanni Grasso
      Pages 125-132

    6. Retinoblastoma: Disease, Diagnosis, Therapy and Management

      • Madhavan Jagadeesan, Sudhir Sudrik, Vikas Khetan
      Pages 133-146

    7. Long-Term Survivors of Retinoblastoma: Risk of Increased Second Malignancy

      • Annette C. Moll, Tamara Marees, Machteld I. Bosscha, Flora E. van Leeuwen
      Pages 147-154

    8. New Cancers Among Long-Term Survivors of Retinoblastoma

      • Alessandro Franchi
      Pages 155-161
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Keywords

About this book

With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targeted—and thus more effective.

Reviews

From the reviews:

“This volume in the series, Tumors of the Central Nervous System, explores recent developments in tumor biology and newer classification and treatment information for seven distinct types of brain tumors. … The book is written for oncologists, both fellows and practitioners, neuro-oncologists, neurologists, neuropathologists, and neurosurgeons. … In addition to providing an update, the book can also inspire a new generation of researchers in tumor biology and in the design of more effective and scientifically based chemotherapy.” (Ramsis Farid Ghaly, Doody’s Review Service, October, 2012)

Editors and Affiliations

  • , Kean University, Room 213, Library building, Union, USA

    M.A. Hayat

Bibliographic Information

  • Book Title: Tumors of the Central Nervous System, Volume 8

  • Book Subtitle: Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma

  • Editors: M.A. Hayat

  • Series Title: Tumors of the Central Nervous System

  • DOI: https://doi.org/10.1007/978-94-007-4213-0

  • Publisher: Springer Dordrecht

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2012

  • Hardcover ISBN: 978-94-007-4212-3Published: 07 June 2012

  • Softcover ISBN: 978-94-024-0601-6Published: 23 August 2016

  • eBook ISBN: 978-94-007-4213-0Published: 14 June 2012

  • Series ISSN: 2215-096X

  • Series E-ISSN: 2215-0978

  • Edition Number: 1

  • Number of Pages: XXXVII, 347

  • Topics: Cancer Research, Oncology, Pathology, Neurosciences, Primary Care Medicine

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