Tumors of the Central Nervous System, Volume 7

1. Front Matter

   Pages i-xxxv

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2. Meningiomas: Molecular Genetics

   1. Front Matter

      Pages 37-37

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3. MENINGIOMAS:Molecular Genetics

   1. Meningiomas: Role of Semaphorin3A Protein in Antiangiogenesis

      • Valeria Barresi

      Pages 3-9

   2. Meningiomas: Role of Carbonic Anhydrase II

      • Katariina Korhonen, Silvia Pastorekova

      Pages 11-15

   3. Meningiomas: Role of Genetic Instabilities of the E-cadherin Gene

      • Nives Pećina-Šlaus

      Pages 17-28

   4. Intracranial Meningiomas: Role of Exogenous Hormones

      • Sudhakar Vadivelu, Michael Schulder

      Pages 29-38

   5. Meningiomas: Clinical Needs and Molecular Insights

      • Saskia Peerdeman, Okay Saydam, Connie Jimenez

      Pages 39-46

   6. Meningioma: Urokinase Plasminogen Activator

      • Venkateswara Rao Gogineni, Arun Kumar Nalla, Jasti S. Rao

      Pages 47-57

   7. miR-200a Regulation of the Wnt Signaling in Meningioma Tumorigenesis

      • Arda Mizrak, Ozlem Senol, Baris Gokhan Ozdener, Okay Saydam

      Pages 59-67

4. Diagnosis

   1. Front Matter

      Pages 69-69

      PDF

   2. Meningiomas: Determination of Subtypes Using Perfusion Magnetic Resonance Imaging

      • Hao Zhang, Guixiang Zhang, Matthijs Oudkerk

      Pages 71-77

   3. Intracranial Meningioma in Mice: Noninvasive Bioluminescence Imaging

      • Brian T. Ragel, Randy L. Jensen

      Pages 79-85

   4. Incidentally Discovered Meningiomas: Growth Rates and Patterns

      • Naoya Hashimoto, Toshiki Yoshimine

      Pages 87-94

   5. Cystic Papillary Meningioma: Diagnosis

      • Zhi Li, Yang Li

      Pages 95-100

   6. Meningioma Tumors: Detection of Subgroups

      • Daniel Monleon, Concha López-Ginés, Rosario Gil-Benso, Jose Manuel González-Darder, Miguel Cerdá-Nicolas

      Pages 101-110

   7. Prognostic Parameters in Atypical and Malignant Meningiomas

      • Joze Pizem, Andrej Cör, Mara Popovic

      Pages 111-118

   8. Sporadic Meningioangiomatosis: Diagnosis with Computed Tomography and Magnetic Resonance Imaging

      • Chi Shing Zee, Zhenwei Yao, Lei Huang

      Pages 119-124

5. Therapy

   1. Front Matter

      Pages 125-125

      PDF

   2. Atypical Meningioma: Distinguishing Features and Role of Adjuvant Radiation

      • Pankaj K. Agarwalla, Manish K. Aghi

      Pages 127-136

   3. Gamma Knife Radiosurgery for Benign Meningioma: Significance and Therapeutic Potential

      • Klaus Haselsberger, Frank Unger

      Pages 137-144

Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume. Insights on the understanding of molecular pathways involved in brain tumor biology are explained. For example, the role of E-cadherin gene instability, carbonic anhydrase 11, urokinase plasminogen activator, and Wnt signaling is discussed in detail. Such information will lead to the development of effective aniicancer drugs. The role of molecular genetics and epigenetic mechanisms in schwannomas is explained. Also, is explained the role of cyclin D1 in vestibular schwannoma. The determination of subtypes of meningiomas using perfusion magnetic resonance imaging is explained. Diagnosis of incidentally discovered meningioma and cystic papillary meningioma is also included. Diagnosis of facial nerve schwannoma, vestibular schwannoma, and intermediate nerve schwannoma is explained. Treatments for atypical meningioma, oncocytic meneingioma, intracranial meningioma, and cavernous are presented. Therapeutic methods such as neurosurgery, Gamma knife radiosurgery, and adjuvant radiation for this cancer are included. Large number of other treatments, including radiosurgery, retrosigmoidal craniotomy, and immunotherapy, for vestibular schwannoma patients are detailed.

• Cancer recurrence
• Immunotherapy
• Meningiomas
• Radiosurgery
• Schwannomas
• antibacterial drug resistance
• Diagnostic Radiology

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  M.A. Hayat

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